| Rank | Student | Grade | School | Year | | STL | G | Total |
| 1 | Danielle Freeman | Sr | Soldan International Studies | 1988-1989 | | 234 | 24 | 9.75 |
| 2 | Kim Woodruff | Sr | St. James | 1996-1997 | | 257 | 27 | 9.52 |
| 3 | Kenna Rae Walker | So | New Bloomfield | 1996-1997 | | 236 | 27 | 8.74 |
| 4 | Kenna Rea Walker | Sr | New Bloomfield | 1988-1989 | | 258 | 31 | 8.32 |
| 5 | Iesia Sutton | Jr | Berkeley High School | 2001-2002 | | 196 | 24 | 8.17 |
| 6 | Jada Bentley | Sr | Beaumont | 2006-2007 | | 173 | 22 | 7.86 |
| 7 | Nikki Ilg | Sr | St. John's Prep High School | 2001-2002 | | 151 | 20 | 7.55 |
| 8 | Jordann Plummer | So | Cardinal Ritter | 2002-2003 | | 179 | 24 | 7.46 |
| 9 | LeAnn Peckham | Sr | Sarcoxie | 1983-1984 | | 200 | 27 | 7.41 |
| 10 | Kim Woodruff | Jr | St. James | 1995-1996 | | 210 | 29 | 7.24 |
| 11 | Donna Simon | Sr | Duchesne | 1995-1996 | | 200 | 28 | 7.14 |
| 12 | Carrie Dickinson | Sr | DeSoto | 1991-1992 | | 194 | 28 | 6.93 |
| 13 | Carlie Sanders | Sr | Hillsboro | 2017-2018 | | 175 | 26 | 6.73 |
| 14 | Kim Woodruff | So | St. James | 1994-1995 | | 208 | 32 | 6.50 |
| 15 | Lacy Stokes | Fr | Mt. Vernon | 2017-2018 | | 183 | 30 | 6.10 |
| 16 | Carlie Sanders | Jr | Hillsboro | 2016-2017 | | 158 | 26 | 6.08 |
| 17 | Maddie Ayers | Fr | South Iron | 2019-2020 | | 171 | 30 | 5.70 |
| 18 | Victoria Nauman | Sr | Mound City | 2018-2019 | | 152 | 28 | 5.43 |