| Rank | BLK | Student | School | Opponent | Date | |
| 1 | 21 | Tori Cole | Twin Rivers | Greenville | 2/20/2012 | |
| 1 | 21 | Adelyne M Dowse | Ballard | Hume | 2/22/2018 | |
| 3 | 20 | | Sikeston | Charleston | 2/16/2026 | |
| 3 | 20 | Marlie Crook | Sikeston | Charleston | 2/16/2026 | |
| 5 | 19 | Sheena Holmer | Tina-Avalon | Tri-County | 2/3/2005 | |
| 6 | 18 | Kathleen Scheer | New Haven | Russellville | 1/10/2007 | |
| 6 | 18 | Cheyenne Baxter | Norborne | Winston | 2/29/2012 | |
| 8 | 17 | Joni Ahern | Atlanta | Linn County | 2/20/2006 | |
| 9 | 16 | Crystal Holbrook | Smithville | Hickman Mills | 1/24/2002 | |
| 9 | 16 | Brooke Flowers | Metro | Villa Duchesne | 1/30/2016 | |
| 11 | 15 | Crystal Holbrook | Smithville | Lafayette (St. Joseph) | 2/20/2003 | |
| 11 | 15 | Jessra Johnson | Fayette | Harrisburg | 12/4/2004 | |
| 11 | 15 | Joni Ahern | Atlanta | Brashear | 2/10/2006 | |
| 11 | 15 | Cheyenne Baxter | Norborne | Northwestern (Mendon) | 2/16/2011 | |
| 11 | 15 | Cheyenne Baxter | Norborne | Albany | 12/27/2011 | |
| 11 | 15 | Callie Schwarzenbach | Kearney | Belton | 1/18/2018 | |
| 11 | 15 | Marlie Crook | Sikeston | Central (New Madrid County) | 1/13/2025 | |
| 18 | 14 | Morgan Johnson | Platte County | Webb City | 3/1/2009 | |
| 19 | 13 | Katie Cordray | Lathrop | Lafayette County | 12/2/2013 | |
| 19 | 13 | Kyrah Lynn Brodie | Rock Bridge | Ozark | 3/11/2020 | |
| 21 | 12 | Katie Cordray | Lathrop | Polo | 1/16/2014 | |
| 21 | 12 | Madison Nelson | Kingston | Valley | 1/25/2022 | |
| 23 | 11 | Lexi Churchill | Hillsboro | | 2/25/2013 | |
| 23 | 11 | Hope Ellsworth | Cainsville | | 12/3/2018 | |
| 23 | 11 | Grace Haase | Lutheran South | Ursuline Academy | 2/4/2021 | |
| 23 | 11 | Brooke Bartholomew | Salisbury | New Franklin | 1/29/2021 | |
| 27 | 10 | Katie Cordray | Lathrop | Maysville | 1/10/2013 | |
| 27 | 10 | Katie Cordray | Lathrop | Bishop LeBlond | 2/26/2014 | |
| 27 | 10 | Joelle Atkins | Cabool | Willow Springs | 1/12/2017 | |
| 27 | 10 | Deidra Sellers | Lathrop | Braymer | 1/25/2017 | |
| 27 | 10 | Joelle Atkins | Cabool | Houston | 1/8/2018 | |
| 27 | 10 | Joelle Atkins | Cabool | Willow Springs | 1/26/2018 | |
| 27 | 10 | Jayda Ann Porter | Rock Bridge | Park Hill South | 3/11/2023 | |
| 27 | 10 | Addison Ridenour | Seymour | Bakersfield | 12/14/2023 | |
| 35 | 9 | Morgan Johnson | Platte County | Miller Career Academy | 3/1/2009 | |
| 35 | 9 | Jayda Ann Porter | Rock Bridge | Vashon | 2/3/2023 | |
| 37 | 8 | Katie Dierdorf | Visitation Academy | Marshfield | 3/1/2002 | |
| 37 | 8 | Brittany Mannings | Duchesne | Notre Dame (Cape Girardeau) | 3/1/2003 | |
| 37 | 8 | Linsay Henke | Blair Oaks | Doniphan | 3/1/2006 | |
| 37 | 8 | Katie Cordray | Lathrop | Penney | 12/14/2012 | |
| 37 | 8 | Katie Cordray | Lathrop | Orrick | 1/7/2013 | |
| 37 | 8 | Baylee Bilyeu | Salem | Ava | 12/8/2015 | |
| 37 | 8 | | Salem | Cabool | 2/5/2015 | |
| 37 | 8 | Baylee Bilyeu | Salem | Willow Springs | 12/28/2017 | |
| 37 | 8 | Baylee Bilyeu | Salem | Mountain Grove | 1/12/2017 | |
| 37 | 8 | Baylee Bilyeu | Salem | St. Clair | 2/20/2017 | |
| 37 | 8 | Baylee Bilyeu | Salem | Ava | 1/29/2018 | |
| 37 | 8 | Reagan Rasmussen | Logan-Rogersville | Springfield Catholic | 2/1/2024 | |
| 37 | 8 | Kamryn Kardosz | Richland | Iberia | 2/2/2025 | |
| 50 | 6 | Stella Mae Baker | Ellington | Naylor | 2/5/2026 | |
| 51 | 5 | Baylee Jo Pugh | Hannibal | Marshall | 1/5/2024 | |