| Rank | Pts | Student | School | Opponent | Date | |
| 1 | 57 | Cadence Pauley | Milan | Green City | 1/7/2019 | |
| 2 | 52 | Lisa Ellis | Elsberry | St. Charles West | 2/17/1981 | |
| 3 | 47 | Jamiah Herring-Green | Hazelwood West | Seckman | 2/21/2025 | |
| 3 | 47 | Lilah Porter | Puxico | Koshkonong | 12/4/2025 | |
| 5 | 44 | Sierra Michaelis | Mercer | Green City | 1/9/2010 | |
| 5 | 44 | Leah Cauble | Oran | South Pemiscot | 12/17/2015 | |
| 5 | 44 | Lilyan Carr | Spokane | Southwest (Washburn) | 1/25/2024 | |
| 8 | 43 | Kaitlyn Belk | Bunker | Kingston | 12/26/2019 | |
| 8 | 43 | Alyce Jaslyn Edwards | Kennett | Central (New Madrid County) | 12/7/2023 | |
| 8 | 43 | Audrie Meyerkorth | Rock Port | Santa Fe | 3/8/2025 | |
| 11 | 42 | Megan Rosenbohm | Nodaway-Holt | Rock Port | 1/21/2011 | |
| 11 | 42 | Gabbie Townsend | Campbell | Southland | 12/4/2024 | |
| 13 | 38 | Chloe Jones | Willow Springs | Van Buren | 1/16/2023 | |
| 14 | 36 | Mallory Moss | Richland | Russellville | 1/27/2024 | |
| 15 | 32 | Parker Ernst | Neelyville | Ellington | 12/29/2022 | |