| Rank | Student | School | Opponent | Date | | FTM | FTA | FT% |
| 1 | Shelby Winkelmann | Hermann | Fair Grove | 3/12/2011 | | 22 | 22 | 100.0% |
| 1 | Lindsey Maple | Knob Noster | Santa Fe | 1/26/2006 | | 19 | 19 | 100.0% |
| 1 | Sarah Woodgeard | Greenville | Clearwater | 1/26/2006 | | 19 | 19 | 100.0% |
| 1 | Brooke Littrell | Green City | Community | 3/6/2020 | | 18 | 18 | 100.0% |
| 1 | Megan Underwood | Thayer | Alton | 2/25/2003 | | 17 | 17 | 100.0% |
| 1 | Mindy Seaton | Putnam County | North Shelby | 2/10/1995 | | 16 | 16 | 100.0% |
| 1 | Lindsey Maple | Knob Noster | Harrisonville Christian Jr. | 11/24/2003 | | 16 | 16 | 100.0% |
| 1 | Kayla Wies | New Franklin | Westran | 1/8/2005 | | 16 | 16 | 100.0% |
| 1 | Leanne Robison | Community | Harrisburg | 3/4/2007 | | 16 | 16 | 100.0% |
| 1 | Emily Holt | Marceline | Kirksville | 1/19/2007 | | 16 | 16 | 100.0% |
| 1 | Addy Roller | Purdy | Fair Grove | 2/16/2012 | | 16 | 16 | 100.0% |
| 1 | Nicole Kost | Mercer | Community | 3/3/2015 | | 16 | 16 | 100.0% |
| 13 | Enzley Dinkins | South Iron | Bunker | 1/4/2022 | | 15 | 16 | 93.8% |
| 14 | Cassidy Hambelton | Dora | Seymour | 2/23/2021 | | 15 | 17 | 88.2% |
| 15 | Skye Beth Uthe | Lathrop | Princeton | 2/17/2020 | | 13 | 16 | 81.3% |
| 16 | Lacy Stokes | Mt. Vernon | Vashon | 3/19/2021 | | 21 | 26 | 80.8% |