| Rank | STL | Student | School | Opponent | Date | |
| 1 | 37 | | Brashear | Macon County | 2/13/2018 | |
| 2 | 36 | | Versailles | Green Ridge | 1/2/2021 | |
| 3 | 35 | | Lathrop | Maysville | 1/11/2000 | |
| 4 | 34 | | Fayette | Marceline | 1/8/2007 | |
| 5 | 33 | | Iberia | Tuscumbia | 1/14/2011 | |
| 5 | 33 | | Macks Creek | Tuscumbia | 12/6/2019 | |
| 7 | 32 | | Jasper | Sheldon | 2/12/2002 | |
| 7 | 32 | | Holcomb | | 1/15/2019 | |
| 9 | 31 | | Santa Fe | Malta Bend | 1/19/1984 | |
| 9 | 31 | | Whitfield | Crossroads College Preparatory | 1/30/1991 | |
| 9 | 31 | | Whitfield | Miller Career Academy | 12/27/1999 | |
| 9 | 31 | | Lathrop | Maysville | 1/9/2001 | |
| 13 | 30 | | South Holt | North Andrew | 2/22/2002 | |
| 13 | 30 | | Fayette | Slater | 12/3/2008 | at Glasgow |
| 13 | 30 | | Elsberry | Wright City | 12/13/2011 | |
| 13 | 30 | | Iberia | Tuscumbia | 1/29/2011 | |
| 13 | 30 | | Scott City | | 1/12/2016 | vs. Delta |
| 18 | 29 | | Scott City | | 11/30/2015 | vs. Delta |
| 19 | 27 | | Portageville | Eugene | 3/1/1992 | |
| 20 | 26 | | Lesterville | | 12/4/2007 | |
| 20 | 26 | | Lesterville | | 1/25/2008 | |
| 22 | 25 | | Scott County Central | Pattonsburg | 3/1/1990 | |
| 23 | 24 | | Greenwood | Wellington-Napoleon | 3/1/1991 | |
| 23 | 24 | | Scott City | | 3/1/2011 | |
| 25 | 23 | | St. Pius X (Festus) | | 12/5/2019 | vs. Valley Park |
| 26 | 22 | | Scott County Central | Newtown-Harris | 3/1/2000 | |
| 26 | 22 | | Jefferson (Conception) | Wheatland | 3/1/2007 | |