| Rank | BLK | Student | School | Opponent | Date | |
| 1 | 21 | Reece Winn | Brunswick | Keytesville | 2/9/2018 | |
| 2 | 20 | Kevin Williams | Nevada | Mt. Vernon | 2/15/1977 | |
| 3 | 19 | Derek Turner | Pierce City | Lockwood | 2/17/2011 | |
| 4 | 18 | Scott White | Englewood Christian | Concordia | 2/10/1989 | |
| 4 | 18 | Tyler Ward | Scott City | Hayti | 1/30/2004 | vs. Hayti |
| 4 | 18 | Cody Stoneburner | North Shelby | Eskridge | 3/8/2005 | |
| 4 | 18 | Justin Ralls | Newtown-Harris | North Harrison | 12/16/2009 | At Winston |
| 8 | 17 | Brian Kelley | Brookfield | Clark County | 3/3/1993 | |
| 8 | 17 | Cody Stoneburner | North Shelby | Novinger | 2/26/2004 | |
| 8 | 17 | Risten Grady | Forsyth | Ava | 2/24/2015 | |
| 11 | 16 | Kevin Williams | Nevada | El Dorado Springs | 1/12/1977 | At Stockton |
| 11 | 16 | Roy McDonald | Hillsboro | Herculaneum | 2/9/1982 | |
| 11 | 16 | Shelby Tonnies | North Shelby | Atlanta | 1/22/1998 | |
| 11 | 16 | David Bancroft | Marshfield | Versailles | 11/30/1999 | |
| 11 | 16 | Cody Stoneburner | North Shelby | Linn County | 11/25/2003 | |
| 11 | 16 | Cody Stoneburner | North Shelby | Scotland County | 2/11/2004 | |
| 11 | 16 | Cody Stoneburner | North Shelby | Linn County | 11/23/2004 | |
| 11 | 16 | Cody Stoneburner | North Shelby | Brashear | 2/22/2005 | |
| 19 | 11 | Robert Liles | Fairfax | Clopton | 3/1/1989 | |
| 20 | 10 | Doug Archer | Jefferson (Conception) | Bell City | 3/1/2007 | |
| 20 | 10 | Lucas Samuel Morrison | Salem | Mountain Grove | 2/24/2021 | |
| 22 | 9 | Darren Baldwin | North Callaway | Hollister | 3/1/1999 | |
| 22 | 9 | Cody Stoneburner | North Shelby | St. Elizabeth | 3/1/2005 | |
| 22 | 9 | Justin Hamrick | Versailles | Boonville | 11/30/2021 | |
| 22 | 9 | Caleb LeGrand | Notre Dame (Cape Girardeau) | Ste. Genevieve | 2/22/2021 | |
| 22 | 9 | Andrew Woodruff | Plato | Stoutland | 2/7/2023 | |
| 27 | 8 | Doug Blissett | Scott County Central | Northeast Nodaway | 3/1/1985 | |
| 27 | 8 | Colin Brown | Braymer | North Shelby | 3/1/2003 | |
| 27 | 8 | Cody Stoneburner | North Shelby | Jefferson (Conception) | 3/1/2005 | |
| 27 | 8 | Caleb LeGrand | Notre Dame (Cape Girardeau) | Poplar Bluff | 2/14/2020 | |
| 27 | 8 | Caleb LeGrand | Notre Dame (Cape Girardeau) | Kennett | 1/15/2021 | |