| Rank | Student | Grade | School | Year | | W | L | PCT |
| 1 | Evan Clark | Sr | Liberty | 2002 | | 31 | 0 | 100.0% |
| 1 | Carson L Haskins | So | Parkway South | 2015 | | 29 | 0 | 100.0% |
| 1 | Mauricio Sovero | Sr | Chaminade | 1992 | | 28 | 0 | 100.0% |
| 1 | Mauricio Sovero | Jr | Chaminade | 1991 | | 27 | 0 | 100.0% |
| 1 | Blake Strode | Sr | Pattonville | 2005 | | 27 | 0 | 100.0% |
| 1 | Casey Smith | Jr | Rockhurst | 1997 | | 26 | 0 | 100.0% |
| 1 | Nick Hegarty | Sr | Central (St. Joseph) | 2003 | | 25 | 0 | 100.0% |
| 1 | Carson L Haskins | Sr | Parkway South | 2017 | | 25 | 0 | 100.0% |
| 1 | Abe Souza | Sr | St. Louis University | 2007 | | 21 | 0 | 100.0% |
| 1 | Carson L Haskins | Fr | Parkway South | 2014 | | 21 | 0 | 100.0% |
| 1 | Carson L Haskins | Jr | Parkway South | 2016 | | 19 | 0 | 100.0% |
| 12 | Andy Metzler | Sr | Rockhurst | 2000 | | 35 | 1 | 97.2% |
| 13 | Caden William Lingenfelser | So | Willard | 2020 | | 32 | 1 | 97.0% |
| 14 | McCasey Smith | Sr | Rockhurst | 1998 | | 27 | 1 | 96.4% |
| 15 | Marko Boskovski | Jr | Parkway North | 2002 | | 26 | 1 | 96.3% |
| 15 | Marko Boskovski | Sr | Parkway North | 2003 | | 26 | 1 | 96.3% |
| 17 | Lucas Emery Riffe | Fr | Republic | 2024 | | 22 | 1 | 95.7% |
| 18 | Caden William Lingenfelser | Jr | Willard | 2021 | Singles | 36 | 2 | 94.7% |
| 19 | Scott Brown | So | Parkway West | 1999 | | 29 | 2 | 93.5% |
| 20 | Garret Lewis | Sr | Joplin | 2018 | | 36 | 4 | 90.0% |
| 21 | Cy Douglas | Sr | Bolivar | 2024 | | 38 | 7 | 84.4% |
| 22 | Bryson Crowell | Jr | Lebanon | 2019 | | 21 | 5 | 80.8% |
| 23 | Jack O'Flaherty | Sr | Rockhurst | 2008 | | 30 | 9 | 76.9% |
| 24 | Kyle Kinderknecht | Sr | Rock Bridge | 2005 | | 28 | 9 | 75.7% |
| 25 | Brendan McKeown | Sr | Mexico | 2023 | | 24 | 8 | 75.0% |