| Rank | Student | School | Years | | G | AST |
| 1 | Blane Brown | Kearney | 2004-2007 | | 107 | 98 |
| 2 | Seth Wiebusch | Harrisonville | 2014-2017 | | 101 | 92 |
| 3 | Ethan David Bromaghim | Orchard Farm | 2017-2020 | | 82 | 79 |
| 4 | Joshua B Udinyiwe | Boonville | 2013-2016 | | 86 | 74 |
| 5 | Cole Harkrader | Harrisonville | 2012-2015 | | 104 | 70 |
| 5 | Gauge Fleschute | Laquey | 2019-2022 | | 98 | 70 |
| 5 | Bodie Rollins | Hannibal | 2021-2024 | | 97 | 70 |
| 8 | Nick Golden | Grandview | 1997-2000 | | 85 | 69 |
| 9 | Caleb Grabill | Harrisonville | 2007-2010 | | 97 | 68 |
| 9 | Hunter Short | Rolla | 2010-2013 | | 112 | 68 |
| 9 | Alec S Adair | Boonville | 2013-2016 | | 86 | 68 |
| 12 | Cory Allensworth | Hannibal | 2014-2017 | | 101 | 65 |
| 12 | Owen Bailey | Pleasant Hill | 2017-2020 | | 83 | 65 |
| 14 | Greg Koeller | St. Thomas Aquinas-Mercy | 1980-1982 | | 84 | 64 |
| 15 | Colton Harden | Marshfield | 2007-2010 | | 93 | 62 |
| 15 | Cody Blentlinger | Harrisonville | 2008-2011 | | 97 | 62 |
| 17 | John Johnson | Christian Brothers College | 1981-1984 | | 100 | 57 |
| 18 | Ethan Larson | Laquey | 2020-2023 | | 93 | 56 |
| 19 | Mark Filla | St. Thomas Aquinas-Mercy | 1991-1994 | | 96 | 54 |
| 19 | Charles Allen | Pembroke Hill | 2007-2010 | | 106 | 54 |
| 19 | Jonathan Najera | Marshall | 2007-2010 | | 100 | 54 |
| 22 | John McQueary | Greenwood | 1994-1997 | | 92 | 53 |
| 23 | Brandon Moore | Rolla | 2002-2004 | | 80 | 50 |
| 24 | Rylen Ballard | Logan-Rogersville | 2018-2021 | | 94 | 46 |
| 25 | Tristen Carriger | Laquey | 2020-2023 | | 75 | 45 |
| 26 | Sage Ballard | Logan-Rogersville | 2018-2021 | | 94 | 40 |