| Rank | Student | School | Opponent | Date | | Goal | AST | TP |
| 1 | Wayne Francis | Fort Osage | Ruskin | 9/21/1990 | | 10 | 1 | 21 |
| 1 | Eric Ooton | St. Pius X (Kansas City) | Maryville | 10/13/2005 | | 10 | 1 | 21 |
| 3 | Evan Burns | Pleasant Hill | Knob Noster | 10/1/2020 | | 9 | 1 | 19 |
| 4 | Ethan Larson | Laquey | Iberia | 10/1/2022 | | 6 | 5 | 17 |
| 5 | Evan Burns | Pleasant Hill | | 9/10/2019 | | 8 | 0 | 16 |
| 6 | John Waddell | Sacred Heart | Calhoun | 9/11/1980 | | 7 | 0 | 14 |
| 6 | Eric Ooton | St. Pius X (Kansas City) | Southern Boone | 9/8/2005 | | 6 | 2 | 14 |
| 6 | Ryan Schliem | Harrisonville | Ruskin | 8/31/2010 | | 7 | 0 | 14 |
| 6 | Braden Remmert | Helias Catholic | Hannibal | 10/3/2015 | | 7 | 0 | 14 |
| 10 | Chris Sellers | Belle | Fatima | 9/30/2005 | | 6 | 1 | 13 |
| 11 | Steve Moss | Windsor (Imperial) | Bayless | 9/10/1996 | (at Pacific) | 6 | 0 | 12 |
| 11 | Jack Jewsbury | Kickapoo | Camdenton | 10/22/1998 | | 6 | 0 | 12 |
| 11 | Nick Golden | Grandview | Ruskin | 10/26/2000 | | 4 | 4 | 12 |
| 11 | J.R. Bizzell | Sikeston | Kennett | 10/16/2003 | | 6 | 0 | 12 |
| 11 | Carson Whittle | Iberia | Stover | 9/29/2020 | | 6 | 0 | 12 |
| 11 | Tristen Carriger | Laquey | Crocker | 10/1/2022 | | 6 | 0 | 12 |
| 11 | Ethan Larson | Laquey | Belle | 9/15/2023 | | 5 | 2 | 12 |
| 11 | Rhyder Martin | Laquey | Aurora | 9/25/2023 | | 5 | 2 | 12 |
| 19 | Tristen Carriger | Laquey | Iberia | 10/1/2022 | | 3 | 5 | 11 |
| 20 | Jaime Andres Villegas | Central (Springfield) | | 9/17/2016 | | 5 | 0 | 10 |
| 20 | Nolan Schulte | Whitfield | Lone Jack | 11/14/2020 | Class 1 | 5 | 0 | 10 |
| 20 | Tristen Carriger | Laquey | Fair Grove | 10/7/2022 | | 5 | 0 | 10 |
| 20 | Tristen Carriger | Laquey | La Monte | 10/13/2023 | | 4 | 2 | 10 |
| 20 | Ethan Larson | Laquey | Aurora | 9/25/2023 | | 4 | 2 | 10 |
| 20 | Ethan Larson | Laquey | Fair Grove | 11/1/2023 | | 5 | 0 | 10 |
| 20 | kayden Hendrix | Laquey | Iberia | 8/31/2023 | | 4 | 2 | 10 |
| 20 | Jack Edward Brinkman | Central (Springfield) | Lebanon | 10/8/2024 | | 5 | 0 | 10 |
| 20 | William Geary | Valley Park | New Heights Christian Acad | 11/20/2024 | Class 1 | 5 | 0 | 10 |
| 20 | Bodie Rollins | Hannibal | Warrenton | 10/24/2024 | | 3 | 4 | 10 |
| 20 | Bodie Rollins | Hannibal | Mexico | 9/24/2024 | | 5 | 0 | 10 |
| 31 | Spencer Joseph Henderson | Central (Springfield) | Parkview | 8/30/2022 | | 3 | 3 | 9 |
| 31 | Jack Edward Brinkman | Central (Springfield) | Neosho | 9/24/2024 | | 4 | 1 | 9 |
| 31 | Bodie Rollins | Hannibal | Mexico | 10/17/2024 | | 3 | 3 | 9 |
| 34 | John Maurer | Lindbergh | Francis Howell North | 11/19/1994 | Class 4A | 4 | 0 | 8 |
| 34 | Jack Edward Brinkman | Central (Springfield) | New Covenant Academy | 9/11/2024 | | 4 | 0 | 8 |
| 34 | Asende Welongo | Rockhurst | Liberty North | 11/23/2024 | Class 4 | 3 | 2 | 8 |
| 37 | Dexter Johnson | Whitefield Academy HS | Pembroke Hill | 11/16/2002 | Class 1 | 3 | 1 | 7 |
| 37 | Adam Stangl | Smithville | New Heights Christian Acad | 11/12/2003 | Class 1 | 2 | 3 | 7 |
| 37 | Brad Peters | St. Dominic | Excelsior Springs | 11/13/2004 | Class 2 | 3 | 1 | 7 |
| 37 | Ross Merrill | Pembroke Hill | Belle | 11/12/2006 | Class 1 | 3 | 1 | 7 |
| 37 | Max David Robertson | Central (Springfield) | Fair Grove | 9/12/2024 | | 2 | 3 | 7 |
| 37 | Jackson Horst | St. Pius X (Kansas City) | New Heights Christian Acad | 11/21/2024 | Class 1 | 3 | 1 | 7 |
| 43 | Mike Stein | St. Thomas Aquinas-Mercy | St. Mary's South Side | 11/15/1996 | Class 1A-3A | 3 | 0 | 6 |
| 43 | Joe Germanese | SLUH | Central (Cape Girardeau) | 11/11/2003 | Class 3 | 3 | 0 | 6 |
| 43 | Michael Ferguson | Pembroke Hill | St. Pius X (Festus) | 11/11/2005 | Class 1 | 2 | 2 | 6 |
| 43 | Sheridan Smith | Webster Groves | Helias Catholic | 11/13/2015 | Class 3 | 3 | 0 | 6 |
| 43 | Elder Reyes | Carthage | Grain Valley | 11/11/2016 | Class 3 | 3 | 0 | 6 |
| 43 | Michael Parrigon | New Heights Christian Acad | Valley Park | 11/20/2024 | Class 1 | 3 | 0 | 6 |