| Rank | Goal | Student | School | Opponent | Date | |
| 1 | 10 | Wayne Francis | Fort Osage | Ruskin | 9/21/1990 | |
| 1 | 10 | Eric Ooton | St. Pius X (Kansas City) | Maryville | 10/13/2005 | |
| 1 | 10 | Jaden Hayes | Maryville | Cameron | 9/2/2019 | |
| 4 | 9 | Evan Burns | Pleasant Hill | Knob Noster | 10/1/2020 | |
| 5 | 8 | Evan Burns | Pleasant Hill | Odessa | 9/10/2019 | |
| 6 | 7 | John Waddell | Sacred Heart | Calhoun | 9/11/1980 | |
| 6 | 7 | Uziel Franco | Cassville | Aurora | 10/25/2008 | |
| 6 | 7 | Ryan Schliem | Harrisonville | Ruskin | 8/31/2010 | |
| 6 | 7 | Braden Remmert | Helias Catholic | Hannibal | 10/3/2015 | |
| 6 | 7 | Brandon MacDonald | Laquey | Osage | 10/11/2018 | |
| 6 | 7 | Evan Burns | Pleasant Hill | Cristo Rey | 8/29/2020 | |
| 6 | 7 | Tucker Jones | Kearney | Raytown South | 10/10/2022 | |
| 13 | 6 | Adam Albright | Hannibal | Moberly | 9/5/2017 | |
| 13 | 6 | Mark Moore | Hillsboro | Moberly | 9/22/2017 | |
| 13 | 6 | Zachary Charles Deibel | Osage | Iberia | 10/1/2018 | |
| 13 | 6 | Carson Whittle | Iberia | Stover | 9/29/2020 | |
| 13 | 6 | Carson Whittle | Iberia | La Monte | 9/7/2021 | at Smithton |
| 13 | 6 | Ethan Larson | Laquey | Iberia | 10/1/2022 | |
| 13 | 6 | Tristen Carriger | Laquey | Crocker | 10/1/2022 | |
| 20 | 5 | Jaime Andres Villegas | Central (Springfield) | Northland Christian | 9/16/2016 | |
| 20 | 5 | Jason S Puente | Monett | Webb City | 10/16/2018 | |
| 20 | 5 | Zachary Cline | Iberia | Crocker | 10/3/2019 | |
| 20 | 5 | Zachary Richards | Lebanon | Dixon | 8/28/2020 | |
| 20 | 5 | Nolan Schulte | Whitfield | Lone Jack | 11/14/2020 | |
| 20 | 5 | Carson Whittle | Iberia | Richland | 11/1/2021 | at Laquey |
| 20 | 5 | Tristen Carriger | Laquey | Fair Grove | 10/7/2022 | |
| 20 | 5 | Ethan Larson | Laquey | Belle | 9/15/2023 | |
| 20 | 5 | Ethan Larson | Laquey | Fair Grove | 11/1/2023 | |
| 20 | 5 | Rhyder Martin | Laquey | Aurora | 9/25/2023 | |
| 20 | 5 | Jack Edward Brinkman | Central (Springfield) | Lebanon | 10/8/2024 | |
| 20 | 5 | Noah Mohmoud | Whitfield | Lutheran North | 10/18/2024 | |
| 20 | 5 | William Geary | Valley Park | New Heights Christian Acad | 11/20/2024 | Class 1 |
| 20 | 5 | Bodie Rollins | Hannibal | Mexico | 9/24/2024 | |
| 34 | 4 | John Maurer | Lindbergh | Francis Howell North | 11/1/1994 | |
| 34 | 4 | Garrett Cole Long | Osage | Belle | 10/15/2018 | |
| 34 | 4 | Kyle Stacey | Fair Grove | Lutheran North | 11/10/2018 | |
| 34 | 4 | Zachary Richards | Lebanon | Parkview | 10/20/2020 | |
| 34 | 4 | Ethan Larson | Laquey | Parkview | 9/2/2022 | |
| 34 | 4 | Ethan Larson | Laquey | Sullivan | 9/20/2022 | |
| 34 | 4 | Ethan Larson | Laquey | Dixon | 11/2/2022 | |
| 34 | 4 | Ethan Larson | Laquey | La Monte | 10/13/2023 | |
| 34 | 4 | Tristen Carriger | Laquey | La Monte | 10/13/2023 | |
| 34 | 4 | Ethan Larson | Laquey | Aurora | 9/25/2023 | |
| 34 | 4 | kayden Hendrix | Laquey | Iberia | 8/31/2023 | |
| 34 | 4 | Jack Edward Brinkman | Central (Springfield) | New Covenant Academy | 9/11/2024 | |
| 34 | 4 | Jack Edward Brinkman | Central (Springfield) | Neosho | 9/24/2024 | |
| 34 | 4 | Riley Lowry | Gateway Science Charter | Gateway Science Charter | 3/31/2025 | |
| 48 | 3 | Mike Stein | Aquinas-Mercy | St. Mary's (STL) | 11/1/1996 | |
| 48 | 3 | Dexter Johnson | Whitfield | Pembroke Hill | 11/1/2002 | |
| 48 | 3 | Joe Germanese | St. Louis University | Central (Cape Girardeau) | 11/1/2003 | |
| 48 | 3 | Brad Peters | St. Dominic | Excelsior Springs | 11/1/2004 | |
| 48 | 3 | Michael Ferguson | Pembroke Hill | St. Pius X (Festus) | 11/1/2005 | |
| 48 | 3 | Ross Merrill | Pembroke Hill | Belle | 11/1/2006 | |
| 48 | 3 | Sheriden Michael Smith | Webster Groves | Helias Catholic | 11/1/2015 | |
| 48 | 3 | Elder Reyes | Carthage | Grain Valley | 11/1/2016 | |
| 48 | 3 | Jason S Puente | Monett | Pembroke Hill | 11/10/2018 | |
| 48 | 3 | Nolan Schulte | Whitfield | Perryville | 11/20/2021 | |
| 48 | 3 | Ethan Larson | Laquey | Iberia | 8/31/2023 | |
| 48 | 3 | Tristen Carriger | Laquey | Iberia | 12/31/2023 | |
| 48 | 3 | Ethan Larson | Laquey | Dixon | 9/13/2023 | |
| 48 | 3 | Jamison Sprunt | Whitfield | St. Mary's South Side | 10/21/2024 | |
| 48 | 3 | Michael Parrigon | New Heights Christian Acad | Valley Park | 11/20/2024 | Class 1 |
| 48 | 3 | Jackson Horst | St. Pius X (Kansas City) | New Heights Christian Acad | 11/21/2024 | Class 1 |
| 48 | 3 | Asende Welongo | Rockhurst | Liberty North | 11/23/2024 | Class 4 |
| 65 | 1 | Abby Lowry | Gateway Science Charter | Gateway Science Charter | 3/31/2025 | |