| Seed | School | Regular Season Record |
| 1 |
Notre Dame (Cape Girardeau)
|
(9-6)
|
| 2 |
Brentwood
|
(12-1)
|
| 3 |
Principia
|
(4-8)
|
| 4 |
Collegiate School of Med-Bio Science
|
(11-6)
|
| 5 |
Bishop DuBourg
|
(3-13)
|
| 6 |
Valley Park
|
(5-8)
|
| 7 |
Lutheran North
|
(3-6)
|
| 8 |
Hancock
|
(6-8)
|
| 9 |
McKinley Classical Leadership
|
(4-10)
|
| 10 |
Crossroads College Preparatory
|
(1-9)
|