| Rank | Student | School | Opponent | Date | | FTM | FTA | FT% |
| 1 | Kaylee DaMitz | Skyline | N/A | 3/1/2018 | | 17 | 17 | 100.0% |
| 1 | Jenna Armstrong | Stockton | N/A | 3/1/2001 | | 15 | 15 | 100.0% |
| 1 | Casey Kraft | Nerinx Hall | N/A | 3/1/2005 | | 15 | 15 | 100.0% |
| 1 | Shari Black | Clopton | N/A | 3/1/1987 | | 14 | 14 | 100.0% |
| 1 | Kyla Burns | Stockton | N/A | 3/1/2003 | | 13 | 13 | 100.0% |
| 1 | Ashley Millham | Notre Dame (Cape Girardeau) | N/A | 3/1/2003 | | 12 | 12 | 100.0% |
| 1 | Casey Garrison | Bolivar | N/A | 3/1/2008 | | 12 | 12 | 100.0% |
| 1 | Kelly McLaughlin | St. Joseph's Academy | N/A | 3/1/2017 | | 12 | 12 | 100.0% |