| Rank | TD | Student | School | Opponent | Date | |
| 1 | 8 | Peyton Jones | Pattonsburg | Braymer | 8/25/2017 | |
| 2 | 7 | Ryder Wilckens-Abney | Concordia | Braymer | 10/8/2021 | |
| 2 | 7 | Tate Kreisel | St. Paul Lutheran (Concordia) | Sweet Springs | 10/4/2024 | |
| 4 | 6 | Zach Sharp | Mound City | North Andrew | 11/22/2003 | at MWSC, 8-Man |
| 4 | 6 | Zach Sharp | Mound City | North Andrew | 3/1/2003 | |
| 4 | 6 | Patrick Cowley | Pattonsburg | | 10/11/2019 | |
| 4 | 6 | Cameron Jones | Pattonsburg | Rich Hill | 10/2/2020 | |
| 4 | 6 | Chase Allen-Jackman | Fayette | Paris | 9/30/2022 | |
| 9 | 5 | Colby Stein | Concordia | | 9/21/2018 | |
| 9 | 5 | Cameron Jones | Pattonsburg | | 10/19/2018 | |
| 9 | 5 | Cameron Jones | Pattonsburg | | 11/9/2018 | |
| 9 | 5 | Cameron Jones | Pattonsburg | Schuyler County | 9/4/2020 | |
| 9 | 5 | Brett Emig | Pattonsburg | Rich Hill | 10/2/2020 | |
| 9 | 5 | Brendyn McDaniel | North Shelby | Northwest (Hughesville) | 9/2/2022 | |
| 9 | 5 | Kolbi Nichols | Drexel | St. Paul Lutheran (Concordia) | 10/20/2023 | |
| 9 | 5 | Gabriel Luke Orr | North Shelby | Paris | 9/8/2023 | |
| 17 | 4 | Troy Brandt | Concordia | | 10/4/2019 | |
| 17 | 4 | Patrick Cowley | Pattonsburg | | 9/20/2019 | |
| 17 | 4 | Zachary D Westmoreland | Joplin | | 11/1/2019 | |
| 17 | 4 | Jobe Bryant | Central (Park Hills) | Central (Park Hills) | 12/1/2023 | |
| 17 | 4 | Jobe Bryant | Central (Park Hills) | Seneca | 12/1/2023 | Class 3 |
| 17 | 4 | Trey Bass | Lutheran North | Festus | 12/6/2024 | Class 4 |
| 17 | 4 | Marshall Kitchen | Westran | Gallatin | 9/27/2024 | |
| 24 | 3 | Percy McBride | Fulton | Richmond | 11/27/1971 | |
| 24 | 3 | Leroy Pruitt | Blue Springs | Parkway Central | 11/28/1992 | |
| 24 | 3 | Dean Meyer | Valle Catholic | Wellington-Napoleon | 11/24/1995 | |
| 24 | 3 | Connor S Basler | Valle Catholic | Marceline | 11/30/2013 | |
| 24 | 3 | Charles Shelton | Pattonville | Staley | 11/25/2017 | Class 5 |
| 24 | 3 | Riley James Brill | Mid-Buchanan | Penney | 11/17/2018 | |
| 24 | 3 | Ethan Hoerr | Southwest (Livingston County) | North Andrew | 11/28/2020 | |
| 24 | 3 | Keelon Smith | Liberty North | Blue Springs | 11/3/2023 | |