| Rank | TD | Student | School | Opponent | Date | |
| 1 | 12 | Steven Willhite | Pattonsburg | | 10/11/2019 | |
| 2 | 10 | Cole Dilley | Pattonsburg | Braymer | 8/25/2017 | |
| 3 | 9 | Koby Reynolds | North Nodaway | Worth County | 9/19/2014 | |
| 3 | 9 | Koby Reynolds | North Nodaway | Worth County | 10/31/2014 | |
| 3 | 9 | Alex Huston | Glendale | Camdenton | 10/16/2015 | |
| 3 | 9 | Alex Huston | Glendale | Springfield Catholic | 10/23/2015 | |
| 3 | 9 | Koby Reynolds | North Nodaway | Rock Port | 8/28/2015 | |
| 3 | 9 | Harrison Andrew Smith | Princeton | Polo | 10/14/2016 | |
| 3 | 9 | Kannon William Nesslage | Kirkwood | Jefferson City | 8/30/2019 | |
| 3 | 9 | Isaac Nieters | Northwest (Hughesville) | Hardin-Central | 10/15/2021 | |
| 3 | 9 | Easton Sheets | St. Paul Lutheran (Concordia) | Sweet Springs | 10/4/2024 | |
| 12 | 8 | Ian Gilworth | Putnam County | Trenton | 11/8/2002 | |
| 12 | 8 | Jordan Webb | Union | Hermann | 9/21/2007 | |
| 12 | 8 | Ryan Howerton | Lebanon | Parkview | 8/29/2008 | |
| 12 | 8 | Alex Huston | Glendale | West Plains | 9/4/2015 | |
| 12 | 8 | Koby Reynolds | North Nodaway | Tarkio | 9/4/2015 | |
| 12 | 8 | Cooper Callis | Jackson | saint louis university high | 10/13/2017 | |
| 12 | 8 | Jacob Powelson | North Andrew | Braymer | 10/13/2017 | 8-Man |
| 12 | 8 | Paxton Joseph Delaurent | Camdenton | Central (Springfield) | 9/20/2019 | |
| 12 | 8 | Carter James King | Skyline | Linn | 10/31/2025 | |
| 21 | 7 | Jeff Handy | Blue Springs | Lee's Summit | 11/3/1989 | 5 in 1st half |
| 21 | 7 | Mitchell Scarbrough | Mound City | North Andrew | 11/22/2003 | at MWSC |
| 21 | 7 | Mitchell Scarbrough | Mound City | North Andrew | 11/1/2003 | |
| 21 | 7 | Jordan Webb | Union | Ozark | 11/7/2007 | |
| 21 | 7 | Scott Anderson | South Holt | Hardin-Central | 9/19/2008 | |
| 21 | 7 | Brendan Weiler | Ste. Genevieve | Potosi | 10/23/2009 | |
| 21 | 7 | Sam Dunbar Van Doren | John Burroughs | Imagine Academy | 10/23/2010 | |
| 21 | 7 | Drew Lock | Lee's Summit | | 11/1/2013 | |
| 21 | 7 | Drew Lock | Lee's Summit | | 8/22/2014 | |
| 21 | 7 | Zane Jacoby | Westran | Schuyler County | 9/12/2014 | |
| 21 | 7 | Alex Huston | Glendale | Joplin | 8/21/2015 | |
| 21 | 7 | Alex Huston | Glendale | Hillcrest | 8/28/2015 | |
| 21 | 7 | Devendra Ahuja | Lutheran North | St. Mary's (St. Louis) | 10/16/2015 | |
| 21 | 7 | Jake Tagtmeyer | Concordia | Braymer | 10/8/2021 | |
| 21 | 7 | Jake Tagtmeyer | Concordia | Braymer | 10/8/2021 | |
| 21 | 7 | Quenton Hughes | Neosho | Willard | 8/26/2022 | |
| 37 | 6 | Travis Miline | South Holt | St. Joseph Christian | 11/1/2004 | |
| 37 | 6 | Brayden McGinnis | Concordia | | 10/4/2019 | |
| 37 | 6 | Kyle T Hays | Monroe City | Van-Far | 10/29/2021 | |
| 37 | 6 | Benjamin Wells | Fayette | Paris | 9/30/2022 | |
| 37 | 6 | Austin Evans | Southern Boone | Eldon | 9/29/2023 | |
| 37 | 6 | Gavin Johnston | Mt. Vernon | Reeds Spring | 11/3/2023 | |
| 37 | 6 | Jonathan Hampton | Wellington-Napoleon | Lone Jack | 9/29/2023 | |
| 44 | 5 | P.J. Sanders | Worth County | North Andrew | 11/1/1995 | |
| 44 | 5 | Judd Naeger | Valle Catholic | Wellington-Napoleon | 11/24/1995 | |
| 44 | 5 | Miles Clifton | Mound City | St. Joseph Christian | 11/1/2008 | |
| 44 | 5 | Thomas Militello | MICDS | Webb City | 11/25/2011 | |
| 44 | 5 | Jaran Richman | Penney | Monroe City | 11/26/2016 | |
| 44 | 5 | Kaleb Eleby | Pattonville | Staley | 11/25/2017 | Class 5 |
| 44 | 5 | Brayden McGinnis | Concordia | | 9/21/2018 | |
| 44 | 5 | Javan Rae Noyes | Mid-Buchanan | West Platte | 10/12/2018 | |
| 44 | 5 | Javan Rae Noyes | Mid-Buchanan | Penney | 11/17/2018 | |
| 44 | 5 | Javen Rae Noyes | Mid-Buchanan | North Platte | 9/25/2020 | |
| 44 | 5 | Javen Rae Noyes | Mid-Buchanan | Maysville | 9/4/2020 | |
| 44 | 5 | Javen Rae Noyes | Mid-Buchanan | Atchison County | 10/16/2020 | |
| 44 | 5 | Javen Rae Noyes | Mid-Buchanan | East Buchanan | 10/9/2020 | |
| 44 | 5 | Kenton Sargent | Windsor | Mid-Buchanan | 12/5/2020 | |
| 44 | 5 | Hunter Hees | Eldon | Versailles | 9/9/2022 | |
| 44 | 5 | Casen Murphy | Central (Park Hills) | Central (Park Hills) | 12/1/2023 | |
| 44 | 5 | Casen Murphy | Central (Park Hills) | Seneca | 12/1/2023 | |
| 44 | 5 | Gage Adler | Westran | Gallatin | 9/27/2024 | |
| 44 | 5 | Brayden Matheney | Hallsville | Macon | 9/20/2024 | |
| 44 | 5 | Brayden Matheney | Hallsville | Winfield | 11/1/2024 | |
| 44 | 5 | Jonathan Moore | Lutheran North | Festus | 12/6/2024 | Class 4 |
| 65 | 4 | Bruce Lilienkamp | Lockwood | King City | 11/30/1974 | |
| 65 | 4 | Eric Ramsey | Warsaw | South Shelby | 11/23/1990 | |
| 65 | 4 | Adam Hinspeter | Centralia | Lawson | 11/28/2003 | |
| 65 | 4 | Drew Newhart | Cameron | Montgomery County | 11/25/2005 | |
| 65 | 4 | Blaine Dalton | Blue Springs South | Christian Brothers College | 11/24/2006 | |
| 65 | 4 | Luke T. Knott | Lee's Summit West | Webster Groves | 11/26/2010 | |
| 65 | 4 | Nolan Wood | Valle Catholic | Marceline | 11/30/2013 | |
| 65 | 4 | Braydn D. Kemper | Mid-Buchanan | Lone Jack | 10/23/2015 | |
| 65 | 4 | Skylar John Thompson | Fort Osage | Chaminade | 11/28/2015 | |
| 65 | 4 | Javan Rae Noyes | Mid-Buchanan | North Platte | 9/14/2018 | |
| 65 | 4 | Josey Dalton Meierarend | Odessa | | 12/7/2019 | |
| 65 | 4 | Javan Rae Noyes | Mid-Buchanan | East Buchanan | 10/4/2019 | |