| Rank | YDS | Student | School | Opponent | Date | |
| 1 | 99 | Dennis Westfall | Marceline | Milan | 10/28/1960 | |
| 1 | 99 | Brock Baker | Bolivar | Salem | 11/8/1995 | |
| 1 | 99 | Brian Lewis | Pattonville | Lafayette (Wildwood) | 9/6/1996 | |
| 1 | 99 | Travis Longwell | Cabool | Houston | 9/5/1997 | |
| 1 | 99 | Chanse Dennis | Trenton | Lathrop | 9/19/1998 | |
| 1 | 99 | Brett Powell | Skyline | Greenfield | 11/10/2004 | |
| 1 | 99 | Scott Concannon | Rock Bridge | Helias Catholic | 10/16/2004 | |
| 1 | 99 | Soloman Watkins | Smith-Cotton | Harrisonville | 10/7/2005 | |
| 1 | 99 | Gabriel M Caine | Parkway North | Parkway West | 10/5/2007 | |
| 1 | 99 | Jaimee Buchanan | Parkway North | Rolla | 11/9/2009 | |
| 1 | 99 | Elbie Fonda | Caruthersville | Portageville | 8/26/2011 | |
| 1 | 99 | Austin Graves | Jefferson (Festus) | Herculaneum | 9/4/2015 | |
| 1 | 99 | Jake Glenn | Central (Park Hills) | Potosi | 9/1/2017 | |
| 1 | 99 | Nathaniel Peat | Rock Bridge | Francis Howell | 10/19/2018 | |
| 1 | 99 | Drake Acheson | Sarcoxie | Pierce City | 9/10/2021 | |
| 1 | 99 | Elijah Stevens | Rockwood Summit | Pacific | 10/28/2022 | |
| 1 | 99 | Jackson P Cheaney | Nevada | Seneca | 10/20/2023 | |
| 1 | 99 | Keyshawn Boyd | Central (Cape Girardeau) | Farmington | 11/10/2023 | |
| 1 | 99 | Jayce DePriest | Warsaw | Sarcoxie | 11/8/2024 | |
| 20 | 98 | Mark Basso | O'Hara | Helias Catholic | 9/25/1971 | |
| 20 | 98 | Trevor Waugh | Marshfield | Bolivar | 9/13/2002 | |
| 20 | 98 | Brian Turntine | Sullivan | Union | 10/10/2003 | |
| 20 | 98 | Matt Verslues | Blair Oaks | Palmyra | 9/3/2004 | |
| 20 | 98 | Scott Concannon | Rock Bridge | Hickman | 9/13/2006 | at Faurot |
| 20 | 98 | Braxton Graham | Seneca | Eldon | 11/16/2013 | |
| 20 | 98 | | Warsaw | Sherwood | 9/15/2023 | |
| 20 | 98 | Jayce DePriest | Warsaw | Sherwood | 9/15/2023 | |
| 28 | 96 | Zacharee E Osborn | Monroe City | Highland | 9/7/2018 | |
| 29 | 94 | Evan Urhahn | Kelly | | 8/25/2017 | |
| 29 | 94 | Avious Steadman | Nevada | Logan-Rogersville | 8/27/2021 | |
| 31 | 93 | Garrett Michael Ferguson | Warsaw | Sherwood | 9/20/2024 | |
| 32 | 92 | Marcus Starks | Bowling Green | Van-Far | 8/27/2021 | |
| 33 | 91 | Matt Prout | Platte County | Salem | 11/30/2002 | |
| 33 | 91 | Trevor Medlin | Lamar | Lafayette County | 11/24/2017 | Class 2 |
| 35 | 90 | Javan Rae Noyes | Mid-Buchanan | Maysville | 9/6/2019 | |
| 36 | 89 | Ronnell Garner | Raytown | Hazelwood East | 11/28/2008 | |
| 37 | 88 | Marcus Starks | Bowling Green | Van-Far | 8/27/2021 | |
| 38 | 87 | Todd Schwent | Valle Catholic | Rock Port | 11/23/1990 | |
| 38 | 87 | Drayden Delong | Eldon | Versailles | 9/9/2022 | |
| 40 | 85 | Robert Vanskike | North Shelby | Drexel | 12/1/1973 | |
| 40 | 85 | Joseph Gouvion | Cassville | Bowling Green | 11/29/2009 | |
| 40 | 85 | Cole R Pennewell | Monroe City | Westran | 11/11/2017 | |
| 40 | 85 | Evan Urhahn | Kelly | | 10/5/2018 | |
| 44 | 84 | Cameren Moore | Eldon | Versailles | 9/9/2022 | |
| 45 | 75 | Daniel Dickerson | Jackson | Platte County | 12/5/2020 | |
| 45 | 75 | Daniel Dickerson | Jackson | Platte County | 12/5/2020 | |
| 47 | 73 | Elijah Lee Mullock | Worth County | Mound City | 11/1/2011 | |
| 48 | 71 | Kyren L. Williams | Vianney | Fort Osage | 12/1/2018 | |
| 49 | 70 | Dylan George | Mound City | Southwest (Livingston County) | 11/30/2019 | |