| Rank | Student | School | Years | | G | Pts |
| 1 | Fred Johnson | Wellsville-Middletown | 1983-1986 | | 120 | 3552 |
| 2 | Bill Roundtree | Wellsville | 1979-1980 | | 118 | 3243 |
| 3 | Brad Parrack | Macks Creek | 1991-1994 | | 118 | 3156 |
| 4 | Tony Osburn | Mound City | 2018-2021 | | 116 | 3080 |
| 5 | Bill Bradley | Crystal City | 1958-1961 | | 112 | 3068 |
| 6 | Brad Hocker | Archie | 1989-1992 | | 104 | 3038 |
| 7 | Michael Isaia Howard | Plattsburg | 2020-2023 | | 114 | 3001 |
| 8 | Jay Lee | Glasgow | 2005-2009 | | 119 | 2999 |
| 9 | Barry Laurie | Versailles | 1975-1978 | | 105 | 2980 |
| 10 | Daniel Cutbirth | Hurley | 1995-1998 | | 108 | 2958 |
| 11 | Logan Thomazin | Walnut Grove | 2014-2017 | | 127 | 2891 |
| 12 | Ryder Joseph Williams | Versailles | 2020-2023 | | 108 | 2877 |
| 13 | Cody Campbell | Montrose | 1995-1998 | | 104 | 2816 |
| 14 | Marcus Walker | O'Hara | 2002-2005 | | 111 | 2789 |
| 15 | Josh Hume | Seymour | 1995-1998 | | 108 | 2786 |
| 16 | Adam Stanley | Princeton | 1989-1993 | | 107 | 2751 |
| 17 | Stump, Arlo | Golden City | 2016-2020 | | 112 | 2734 |
| 18 | Aminu Mohammed | Greenwood | 2018-2020 | | 87 | 2709 |
| 19 | Drenin Dinkins | South Iron | 2018-2021 | | 118 | 2646 |
| 20 | Monty Johal | Glendale | 2014-2017 | | 111 | 2584 |
| 21 | Jordan Fuemmeler | Glasgow | 2020-2023 | | 112 | 2571 |
| 22 | Derek Rockett | Higbee | 2020-2023 | | 111 | 2512 |
| 23 | Dale Stanley | Licking | 1964-1967 | | 118 | 2494 |
| 24 | Lane Duncan | Licking | 2011-2014 | | 112 | 2441 |
| 25 | Andrew Dalton | Ava | 2018-2021 | | 111 | 2431 |
| 26 | Benjamin M Denbow | Licking | 2008-2012 | | 114 | 2392 |
| 26 | Benjamin M Denbow | Licking | 2008-2012 | | 114 | 2392 |
| 28 | Carter Trumbore | Butler | 2020-2023 | | 107 | 2382 |
| 29 | Blake Fowler | Campbell | 2017-2020 | | 108 | 2345 |
| 30 | Clayton Parker | Montgomery County | 2021-2024 | | 119 | 2281 |
| 31 | Rafe Kalberloh | Lakeland | 2017-2021 | | 113 | 2237 |
| 32 | John Fleeman | Kingsville | 2022-2025 | | 115 | 2217 |
| 33 | Sam Richardson Jr. | Hancock | 2016-2019 | | 104 | 2176 |
| 34 | Cody Jones | Galena | 2022-2025 | | 107 | 2145 |
| 35 | Sam Simpson | Thomas Jefferson Independent Day | 2004-2007 | | 104 | 2141 |
| 36 | Drew Apsher | Smithton | 2013-2016 | | 104 | 2130 |
| 37 | Nathan Burnett | Risco | 2015-2018 | | 107 | 2109 |
| 38 | Caleb Coen Brown | Sacred Heart | 2018-2021 | | 109 | 2105 |
| 39 | Daniel Presley | Risco | 1996-1999 | | 90 | 2078 |
| 40 | Corbin Joe Axtell | Grundy County | 2020-2024 | | 110 | 2073 |
| 41 | Lane Dunlap | Golden City | 2017-2020 | | 113 | 2068 |
| 41 | Brock Wakefield | South Iron | 2017-2020 | | 106 | 2068 |
| 43 | Michael Russell | McDonald County | 1994-1997 | | 104 | 2065 |
| 44 | Chase Parrish | Montgomery County | 2013-2016 | | 109 | 2054 |
| 45 | Jacob Richard Elmore-Stellwagen | Montgomery County | 2020-2023 | | 111 | 2046 |
| 46 | Kiefer Tolson | Trenton | 2021-2024 | | 97 | 2043 |
| 47 | Jackson Meyer | Glasgow | 2025-2026 | | 113 | 2039 |
| 48 | Trenton Jameson McBride | Eminence | 2015-2019 | | 120 | 2036 |
| 49 | Landan Burchard | Puxico | 2022-2025 | | 110 | 2025 |
| 50 | Luke Northweather | Blair Oaks | 2018-2021 | | 102 | 2018 |
| 51 | Trenton Lyles | Sacred Heart | 2014-2017 | | 118 | 2007 |
| 52 | Gage Johnson | Weaubleau | 2020-2023 | | 117 | 1997 |
| 53 | Alex Oserowsky | Thomas Jefferson Independent Day | 2008-2011 | | 102 | 1953 |
| 54 | Isaac Bird | Gallatin | 2020-2023 | | 107 | 1948 |
| 55 | Jon Samuel Smith | Risco | 2021-2024 | | 95 | 1942 |
| 56 | Jordan Walton | Glendale | 2014-2017 | | 111 | 1936 |
| 57 | Andrew Almany | Licking | 2000-2003 | | 106 | 1885 |
| 58 | Trent Smith | Carl Junction | 2015-2018 | | 97 | 1829 |
| 59 | Jordon Pavy | Risco | 2010-2013 | | 108 | 1786 |
| 60 | Casey Knight | Risco | 1995-1998 | | 76 | 1740 |
| 61 | Grant Clemons | Thomas Jefferson Independent Day | 1996-1999 | | 76 | 1567 |
| 62 | Amare Witham | Glendale | 2022-2023 | | 55 | 1207 |