| Rank | Total | School | Years |
| 1 | 29 | St. Joseph's Academy | 1976, 1977, 1982, 1983, 1984, 1986, 1991, 1993 (2), 1994, 1995, 1996, 1997, 1998, 1999, 2000, 2001, 2005, 2006 (2), 2007, 2008, 2011, 2018, 2019, 2020, 2022, 2023, 2025 |
| 2 | 23 | John Burroughs | 1986, 1988, 1989 (2), 1991, 2001, 2003, 2004, 2005, 2006, 2007, 2008, 2009, 2010, 2011, 2016, 2017 (2), 2018, 2019 (2), 2020, 2021 |
| 3 | 15 | Barstow | 1975, 1977, 1980, 1995, 1996, 2007, 2008, 2011, 2012, 2013, 2015, 2016, 2021 (2), 2024 |
| 4 | 14 | Rock Bridge | 1982, 1983, 1999, 2001, 2002, 2003, 2004 (2), 2012, 2016, 2017, 2018, 2024, 2025 |
| 5 | 13 | Pembroke Hill | 1990 (2), 1991, 1992, 1994, 1995, 1997, 2004, 2005, 2006, 2014, 2015, 2018 |
| 6 | 12 | Ladue Horton Watkins | 1989, 1990, 1991, 1992, 1996, 2010 (2), 2022 (2), 2024, 2025 (2) |
| 7 | 10 | Visitation Academy | 1985, 1986, 1987 (2), 1988, 2003, 2010, 2012, 2020 (2) |
| 8 | 8 | MICDS | 1997, 1998 (2), 1999, 2000 (2), 2002, 2023 |
| 9 | 5 | Jefferson City | 1987, 1988, 1992, 1994, 1995 |
| 9 | 5 | Clayton | 1985, 2001, 2002, 2014, 2022 |
| 9 | 5 | Lafayette (Wildwood) | 2007, 2014, 2015, 2016, 2023 |
| 12 | 4 | Bishop LeBlond | 1978, 1979, 1980, 1981 |
| 13 | 3 | Lee's Summit | 1986, 1987, 2013 |
| 13 | 3 | Lindbergh | 1981, 1984, 2015 |
| 13 | 3 | Villa Duchesne | 1993, 2013, 2020 |
| 13 | 3 | Kennett | 2022, 2023, 2024 |
| 17 | 2 | Webster Groves | 1976, 1979 |
| 17 | 2 | Carthage | 1989, 1990 |
| 17 | 2 | Chillicothe | 1992, 1996 |
| 17 | 2 | St. Teresa's Academy | 2002, 2003 |
| 17 | 2 | Joplin | 1998, 2005 |
| 17 | 2 | Parkway Central | 1997, 2011 |
| 17 | 2 | Kirkwood | 2009, 2013 |
| 17 | 2 | Liberty | 2019, 2024 |
| 17 | 2 | Bolivar | 2020, 2025 |