| Rank | Total | Student | School | Opponent | Date | |
| 1 | 28 | Brody Langfitt | Pattonsburg | North Andrew | 9/11/2020 | |
| 2 | 23 | Kyle Cotter | Windsor (Imperial) | Seckman | 10/2/2009 | |
| 2 | 23 | Cameron Jones | Pattonsburg | St. Paul Lutheran (Concordia) | 10/16/2020 | |
| 4 | 21 | Jakob Cordell | North Nodaway | Rock Port | 8/28/2015 | |
| 4 | 21 | Daytona Lutz-Dobbins | North Nodaway | Rock Port | 8/28/2015 | |
| 4 | 21 | Brett Emig | Pattonsburg | King City | 9/18/2020 | |
| 7 | 20 | Dustin Noll | Ste. Genevieve | Fredericktown | 10/30/2008 | |
| 7 | 20 | Dustin Noll | Ste. Genevieve | Central (New Madrid County) | 11/10/2008 | |
| 7 | 20 | Patrick Cowley | Pattonsburg | | 10/18/2019 | |
| 10 | 19 | Matt Hans | Montgomery County | Bowling Green | 9/9/2003 | |
| 10 | 19 | Luke S Montgomery | Glendale | Rolla | 10/2/2015 | |
| 10 | 19 | Isaiah Green | Neosho | Willard | 8/26/2022 | |
| 13 | 18 | Mitch Guemmer | DeSoto | St. Clair | 10/1/2004 | |
| 13 | 18 | Chris Sperry | Union | Owensville | 10/12/2007 | |
| 13 | 18 | Brett Emig | Pattonsburg | Rich Hill | 10/2/2020 | |
| 16 | 17 | Cameron Jones | Pattonsburg | Rich Hill | 10/2/2020 | |
| 17 | 16 | Eric Anderson | Cameron | Savannah | 11/6/2003 | |
| 17 | 16 | Phillip Archer | Lebanon | Kickapoo | 9/25/2008 | |
| 17 | 16 | Luke S Montgomery | Glendale | Hillcrest | 8/28/2015 | |
| 17 | 16 | Stetson E. Brant | Mid-Buchanan | North Platte | 9/4/2015 | |
| 17 | 16 | Antonio Burks Jr. | St. Mary's (St. Louis) | Westminster Christian Academy | 8/20/2016 | |
| 17 | 16 | Cristian Velasquez | Sarcoxie | Sarcoxie | 10/4/2019 | |
| 17 | 16 | Isaiah Green | Neosho | Carl Junction | 9/9/2022 | |
| 17 | 16 | Isaiah Green | Neosho | Ozark | 10/7/2022 | |
| 17 | 16 | Brock Franklin | Neosho | Willard | 10/28/2022 | |
| 26 | 15 | Eli Klenke | Union | | 9/8/2017 | Vs. Pacific |
| 26 | 15 | Cameron Jones | Pattonsburg | King City | 9/18/2020 | |
| 26 | 15 | Jobe Bryant | Central (Park Hills) | Seneca | 12/1/2023 | |
| 29 | 14 | Eric Anderson | Cameron | Blair Oaks | 11/26/2004 | |
| 29 | 14 | Stetson E. Brant | Mid-Buchanan | Lone Jack | 10/23/2015 | |
| 29 | 14 | Eli Klenke | Union | | 9/1/2017 | |
| 32 | 13 | Jack Howell | MICDS | Webb City | 11/25/2011 | |
| 32 | 13 | Stetson E. Brant | Mid-Buchanan | Lathrop | 10/16/2015 | |
| 32 | 13 | Cameron Jones | Pattonsburg | Albany | 10/23/2020 | |
| 35 | 12 | Derick Newby | Webb City | Kearney | 11/27/2015 | |
| 35 | 12 | Stetson E. Brant | Mid-Buchanan | King City | 8/21/2015 | |
| 35 | 12 | Chase M. Gilbert | Mid-Buchanan | Lawson | 10/9/2015 | |
| 35 | 12 | Cameron Jones | Pattonsburg | Stanberry | 9/25/2020 | |
| 35 | 12 | Chase Allen-Jackman | Fayette | Salisbury | 10/7/2022 | |
| 35 | 12 | Jobe Bryant | Central (Park Hills) | Central (Park Hills) | 12/1/2023 | |
| 41 | 11 | Wes Kamp | DeSmet | Hazelwood Central | 11/25/2005 | |
| 41 | 11 | Stetson E. Brant | Mid-Buchanan | Penney | 9/11/2015 | |
| 43 | 10 | Ben Longstreet | Montgomery County | Cameron | 11/25/2005 | |
| 43 | 10 | Zachary T Weiler | Valle Catholic | Westran | 11/26/2010 | |
| 43 | 10 | Foster Bundy | MICDS | Webb City | 11/25/2011 | |
| 43 | 10 | Mitchell Officer | North Andrew | Stanberry | 3/1/2015 | |
| 43 | 10 | Landon Hahs | Kelly | | 10/6/2017 | |
| 43 | 10 | Landon Hahs | Kelly | | 10/13/2017 | |
| 43 | 10 | Christian Blake Scaggs | Mid-Buchanan | Penney | 9/21/2018 | |
| 50 | 9 | Zach Sharp | Mound City | North Andrew | 3/1/2003 | |
| 50 | 9 | James T. Dunn | Mid-Buchanan | West Platte | 9/30/2016 | |
| 50 | 9 | Matthew McDonald | Mid-Buchanan | Maysville | 8/25/2017 | |
| 50 | 9 | Christian Blake Scaggs | Mid-Buchanan | West Platte | 10/12/2018 | |
| 54 | 8 | Matt Gilliland | Southwest (Livingston County) | Nodaway-Holt | 3/1/1990 | |
| 54 | 8 | Stephen Corkins | St. Joseph Christian | South Holt | 3/1/2004 | |
| 54 | 8 | Caden Casey | Central (Park Hills) | Central (Park Hills) | 12/1/2023 | |
| 54 | 8 | Kannon Harlow | Central (Park Hills) | Central (Park Hills) | 12/1/2023 | |
| 54 | 8 | Kannon Harlow | Central (Park Hills) | Seneca | 12/1/2023 | 8 for 124, 1 TD |
| 54 | 8 | Caden Casey | Central (Park Hills) | Seneca | 12/1/2023 | 8 for 140 |
| 60 | 7 | Braydon Berry | Central (Park Hills) | Seneca | 12/1/2023 | |