| Rank | Student | School | Years | | K | E | ATT | PCT |
| 1 | Raylee Stenzel | Mountain Grove | 2021-2024 | | 4923 | 678 | 4923 | .862 |
| 2 | Kristin Folkl | St. Joseph's Academy | 1990-1993 | | 1819 | 385 | 2976 | .482 |
| 3 | Tessa Jones | O'Hara | 2000-2003 | | 1908 | 248 | 3555 | .467 |
| 4 | Stephanie Campbell | Lafayette (Wildwood) | 2010-2012 | | 756 | 112 | 1438 | .448 |
| 5 | Marissa Hundelt | Orchard Farm | 2006-2009 | | 1165 | 160 | 2322 | .433 |
| 6 | Adriene Francis | Exeter | 1998-2000 | | 487 | 54 | 1024 | .423 |
| 7 | Heather Kea | Westminster Christian Academy | 1996-1999 | | 943 | 166 | 1921 | .404 |
| 8 | Allison Nicole Beaton | Lafayette (Wildwood) | 2017-2019 | | 503 | 109 | 1013 | .389 |
| 9 | Bella Grace Scherfenberg | Belton | 2022-2025 | | 1497 | 380 | 2926 | .382 |
| 10 | Bennett Raterman | St. Pius X (Festus) | 2022-2025 | | 1556 | 385 | 3098 | .378 |
| 11 | Taylor Cook | Lesterville | 2008-2011 | | 1484 | 294 | 3169 | .376 |
| 12 | Taylor Golmen | Nixa | 2017-2020 | | 692 | 128 | 1532 | .368 |
| 13 | Katie Kieffer | St. Joseph's Academy | 1995-1998 | | 696 | 141 | 1516 | .366 |
| 14 | Lily Johnson | Lafayette (Wildwood) | 2010-2013 | | 974 | 233 | 2084 | .356 |
| 15 | Emma Siron | Sacred Heart | 2019-2022 | | 1737 | 474 | 3586 | .352 |
| 16 | Rebekah Wedick | Willow Springs | 1996-1999 | | 1123 | 336 | 2238 | .352 |
| 17 | Emily Moore | Bernie | 1994-1997 | | 546 | 147 | 1140 | .350 |
| 18 | Jamie Roszell | East Newton | 1995-1998 | | 1303 | 353 | 2751 | .345 |
| 19 | Emily Carr | Cameron | 2008-2011 | | 1021 | 234 | 2295 | .343 |
| 20 | Kelsey Stewart | Mt. Vernon | 2002-2005 | | 774 | 187 | 1737 | .338 |
| 21 | Janah Heits | Fairfax | 1999-2002 | | 723 | 144 | 1716 | .337 |
| 22 | Chloe Judd | Nixa | 2021-2024 | | 728 | 208 | 1610 | .323 |
| 23 | Cameron Layne Dake | Mt. Vernon | 2012-2015 | | 1190 | 380 | 2561 | .316 |