| Rank | School | Year | | Sets | ACE |
| 1 | Collegiate School of Med-Bio Science | 2025 | | 94 | 562 |
| 2 | Clarkton | 2024 | | 111 | 405 |
| 3 | Clarkton | 2022 | | 110 | 398 |
| 4 | Clarkton | 2023 | | 106 | 374 |
| 5 | Clarkton | 2021 | | 109 | 352 |
| 6 | Bunker | 2021 | | 104 | 347 |
| 7 | Holden | 1994 | | 53 | 335 |
| 8 | Jefferson (Festus) | 2021 | | 116 | 330 |
| 9 | Carl Junction | 2023 | | 105 | 328 |
| 10 | Blair Oaks | 2021 | | 105 | 317 |
| 11 | Lafayette (Wildwood) | 2023 | | 108 | 308 |
| 12 | Jefferson (Festus) | 2022 | | 108 | 306 |
| 13 | Hollister | 2024 | | 110 | 296 |
| 14 | Pattonville | 2000 | | 77 | 293 |
| 15 | East Buchanan | 2023 | | 106 | 290 |
| 16 | Bolivar | 2022 | | 106 | 283 |
| 16 | Bolivar | 2022 | | 106 | 283 |
| 18 | East Buchanan | 2022 | | 114 | 279 |
| 19 | Lafayette (Wildwood) | 2024 | | 107 | 277 |
| 20 | Holden | 1995 | | 81 | 275 |
| 21 | Fairfax | 2001 | | 80 | 268 |
| 22 | Thomas Jefferson Independent | 1998 | | 69 | 263 |
| 23 | Bolivar | 2021 | | 101 | 259 |
| 24 | Fairfax | 2000 | | 74 | 257 |
| 25 | Bolivar | 2023 | | 107 | 256 |
| 26 | Staley | 2025 | | 101 | 255 |
| 27 | Cameron | 2010 | | 78 | 248 |
| 28 | Mt. Vernon | 2022 | | 95 | 247 |
| 29 | Bolivar | 2025 | | 87 | 240 |
| 30 | South Holt | 1998 | | 68 | 238 |
| 31 | Jefferson (Festus) | 2019 | | 75 | 235 |
| 32 | Staley | 2024 | | 106 | 214 |
| 33 | Staley | 2023 | | 86 | 208 |
| 34 | Cameron | 2011 | | 73 | 23 |