| Rank | Student | School | Year | | ACE | Sets | AVG |
| 1 | | Holden | 1994 | | 335 | 53 | 6.32 |
| 2 | | Collegiate School of Med-Bio Science | 2025 | | 562 | 94 | 5.98 |
| 3 | | Thomas Jefferson Independent | 1998 | | 263 | 69 | 3.81 |
| 4 | | Pattonville | 2000 | | 293 | 77 | 3.81 |
| 5 | | Holden | 1993 | | 205 | 54 | 3.80 |
| 6 | | Clarkton | 2024 | | 405 | 111 | 3.65 |
| 7 | | Clarkton | 2022 | | 398 | 110 | 3.62 |
| 8 | | Clarkton | 2023 | | 374 | 106 | 3.53 |
| 9 | | Holden | 1995 | | 285 | 81 | 3.52 |
| 10 | | South Holt | 1998 | | 238 | 68 | 3.50 |
| 11 | | Fairfax | 2000 | | 257 | 74 | 3.47 |
| 12 | | Fairfax | 2002 | | 229 | 66 | 3.47 |
| 13 | | Fairfax | 2001 | | 268 | 80 | 3.35 |
| 14 | | Lafayette (Wildwood) | 1995 | | 221 | 66 | 3.35 |
| 15 | | Bunker | 2021 | | 347 | 104 | 3.34 |
| 16 | | Clarkton | 2021 | | 352 | 109 | 3.23 |
| 17 | | Jefferson (Festus) | 2019 | | 235 | 75 | 3.13 |
| 18 | | Carl Junction | 2023 | | 328 | 105 | 3.12 |
| 19 | | Blair Oaks | 2021 | | 317 | 105 | 3.02 |
| 20 | | Lafayette (Wildwood) | 2023 | | 308 | 108 | 2.85 |
| 21 | | Jefferson (Festus) | 2021 | | 330 | 116 | 2.84 |
| 22 | | Jefferson (Festus) | 2022 | | 306 | 108 | 2.83 |
| 23 | | East Buchanan | 2023 | | 290 | 106 | 2.74 |
| 24 | | Hollister | 2024 | | 296 | 110 | 2.69 |
| 25 | | Bolivar | 2022 | | 283 | 106 | 2.67 |
| 26 | | Mt. Vernon | 2022 | | 247 | 95 | 2.60 |
| 27 | | Lafayette (Wildwood) | 2024 | | 277 | 107 | 2.59 |
| 28 | | Bolivar | 2021 | | 259 | 101 | 2.56 |
| 29 | | East Buchanan | 2022 | | 279 | 114 | 2.45 |
| 30 | | Staley | 2023 | | 208 | 86 | 2.42 |
| 31 | | Bolivar | 2023 | | 256 | 107 | 2.39 |
| 32 | | Staley | 2024 | | 214 | 106 | 2.02 |