| Rank | Student | School | Years | | Sets | AST |
| 1 | Lexi Lynn Lindsey | Winona | 2022-2025 | | 432 | 4246 |
| 2 | Elena Dano Ruble | St. Pius X (Festus) | 2022-2025 | | 376 | 4111 |
| 3 | Sydney Brooke Golden | Nixa | 2018-2021 | | 378 | 3920 |
| 4 | Brinley Cowart | Clarkton | 2021-2024 | | 436 | 3811 |
| 5 | Carley Nicholson | St. Pius X (Festus) | 2014-2017 | | 328 | 3722 |
| 6 | Katelyn Diani-O'Day | Lutheran St. Charles | 2021-2024 | | 443 | 3568 |
| 7 | Logan Ryann Jones | Carl Junction | 2019-2022 | | 355 | 3503 |
| 8 | Reece Anne Cook | Ozark | 2021-2024 | | 323 | 3430 |
| 9 | Danika Wattenbarger | St. Joseph Christian | 2020-2023 | | 362 | 3289 |
| 10 | Alyssa Nelson | Lafayette (Wildwood) | 2020-2023 | | 319 | 3203 |
| 11 | Gracie Hicks | Lesterville | 2019-2022 | | 382 | 3139 |
| 12 | Isabella Gracyn Asante | Camdenton | 2022-2025 | | 395 | 3103 |
| 13 | Abby Chadwell | Strafford | 2019-2022 | | 377 | 3099 |
| 14 | Alli Mitchell | Miller | 2018-2021 | | 344 | 3085 |
| 15 | Macey Browers | Arcadia Valley | 2015-2018 | | 310 | 3030 |
| 16 | Alexa Marie Ethridge | Lee's Summit North | 2009-2012 | | 321 | 2973 |
| 17 | Alaina Nicole Saunders | Belton | 2019-2022 | | 336 | 2972 |
| 18 | Sydney Brooke Golden | Nixa | 2018-2020 | | 277 | 2839 |
| 19 | Jenny Orf | Lafayette (Wildwood) | 2000-2003 | | 290 | 2834 |
| 20 | Sophie Whitesell | Lockwood | 2005-2008 | | 302 | 2801 |
| 21 | Paige Alyssa Siebert | Jefferson (Festus) | 2019-2022 | | 345 | 2767 |
| 22 | Olivia Lotz | Timberland | 2014-2017 | | 292 | 2759 |
| 23 | Shannon Ayer | Notre Dame de Sion | 1999-2002 | | 314 | 2728 |
| 24 | Amy Lindhorst | Oak Park | 2009-2012 | | 298 | 2633 |
| 25 | Malerie Lynn Sharp | Gideon | 2018-2021 | | 290 | 2529 |
| 26 | Sarah Mueller | Santa Fe | 1994-1997 | | 191 | 2515 |
| 27 | Hannah Joyce | Pleasant Hill | 2018-2020 | | 253 | 2505 |
| 28 | Kendra N Sater | Ozark | 2012-2015 | | 364 | 2501 |
| 29 | Emma Klein | East Buchanan | 2018-2021 | | 300 | 2439 |
| 29 | Emma Klein | East Buchanan | 2018-2021 | | 300 | 2439 |
| 31 | Taryn Nash | Truman | 2006-2009 | | 309 | 2425 |
| 32 | Kylie Aiko Hunter | Stockton | 2019-2023 | | 347 | 2409 |
| 33 | Erin Moore | Bernie | 1992-1995 | | 307 | 2366 |
| 34 | Maggie Scott | Lafayette (Wildwood) | 2011-2013 | | 249 | 2279 |
| 35 | Kenna O'Riley | Bishop LeBlond | 2016-2019 | | 312 | 2260 |
| 36 | Lexi Ferguson | Mid-Buchanan | 2021-2024 | | 362 | 2174 |
| 37 | Payton Woodrum | Mt. Vernon | 2012-2015 | | 284 | 2015 |
| 37 | Payton Woodrum | Mt. Vernon | 2012-2020 | | 284 | 2015 |
| 39 | Kylie Clark | East Buchanan | 2020-2023 | | 254 | 2004 |
| 40 | Bailey Myers | Lesterville | 2014-2017 | | 292 | 2002 |
| 41 | Jacy Bray | Nixa | 2020-2023 | | 215 | 1963 |
| 42 | Ashley Hydorn | Oak Park | 1999-2002 | | 302 | 1955 |
| 43 | Erin McClanahan | Cor Jesu Academy | 1999-2001 | | 188 | 1954 |
| 44 | Rielly Dobbs | Nixa | 2012-2015 | | 216 | 1945 |
| 45 | Lacy Stokes | Mt. Vernon | 2017-2020 | | 317 | 1928 |
| 46 | Tedi Thoreson | El Dorado Springs | 1999-2002 | | 293 | 1913 |
| 47 | Abigail Cole | Licking | 2016-2019 | | 291 | 1844 |
| 48 | Hannah Nicole Vaughn | Poplar Bluff | 2015-2017 | | 224 | 1809 |
| 49 | Cali Bailey | Mid-Buchanan | 2017-2019 | | 217 | 1787 |
| 50 | Madeline Yahnig | Midway | 2015-2018 | | 283 | 1784 |
| 51 | Kira Phipps | Lawson | 2020-2022 | | 259 | 1743 |
| 52 | Macie West | Mt. Vernon | 2022-2024 | | 269 | 1662 |
| 53 | Hallie Tucker | Bolivar | 2018-2020 | | 236 | 1646 |
| 54 | Lexie Malam | Houston | 2003-2006 | | 217 | 1623 |
| 55 | Halayna Loyd | Jefferson (Festus) | 2023-2025 | | 262 | 1531 |
| 56 | Natalie Emro | Lafayette (Wildwood) | 2005-2006 | | 143 | 1496 |
| 57 | Lauren Hyde | Mid-Buchanan | 2013-2016 | | 275 | 1436 |
| 58 | Emily Powell | Midway | 2018-2022 | | 287 | 1406 |
| 59 | Megan Howard | Bolivar | 2021-2024 | | 395 | 1359 |
| 60 | Raelin Swillum | Mt. Vernon | 2016-2018 | | 226 | 1347 |
| 61 | Katie Hyneman | Oak Park | 2005-2006 | | 147 | 1235 |
| 62 | Jessie Humbird | Midway | 2017-2020 | | 207 | 1221 |
| 63 | Bethanie Nicole Funderburk | Nixa | 2006-2009 | 3 Years | 163 | 1206 |
| 64 | Miya Carnes | Carl Junction | 2022-2023 | | 120 | 1173 |
| 65 | Gracie Fish | Jefferson (Festus) | 2016-2018 | | 167 | 1135 |
| 66 | Lillie May Anne Ricketts | Miller | 2019-2022 | | 165 | 943 |
| 67 | Elliana Partin | Bolivar | 2020-2022 | | 207 | 887 |
| 68 | Shelby Roberts | Bolivar | 2010-2013 | | 145 | 788 |
| 69 | Raynabeth Wilson | Bolivar | 2021-2024 | | 195 | 748 |
| 70 | Kylie Taylor | Licking | 2018-2021 | | 320 | 743 |