| Rank | Student | School | Years | | G | 3B |
| 1 | Mason Adams | Portageville | 2020-2024 | | 143 | 20 |
| 2 | Austin Schmitt | Valley Park | 2014-2017 | | 109 | 19 |
| 3 | Kevin Addington | Nevada | 1990-1992 | | 66 | 17 |
| 3 | Nick Andriano | Mid-Buchanan | 2008-2011 | | 64 | 17 |
| 3 | Wyatt Michael Vincent | Nixa | 2021-2024 | | 114 | 17 |
| 6 | Johnny Eierman | Warsaw | 2006-2010 | | 79 | 16 |
| 6 | Johnny Eierman | Warsaw | 2006-2010 | | 79 | 16 |
| 8 | Nathan Geile | Valle Catholic | 2007-2010 | | 116 | 15 |
| 9 | Ryan Rallo | Christian Brothers College | 1997-2000 | | 95 | 14 |
| 10 | Blake DeWitt | Sikeston | 2001-2004 | | 107 | 13 |
| 10 | Tyler Ketterman | Nevada | 2013-2016 | | 89 | 13 |
| 12 | Nick Wilfong | Francis Howell | 1996-1997 | | 56 | 12 |
| 12 | Jake Whitesides | Hickman | 1997-2000 | | 100 | 12 |
| 12 | Ryan Sheffield | Carl Junction | 1998-2001 | | 88 | 12 |
| 12 | Tim Trout | Monett | 2003-2006 | | 79 | 12 |
| 12 | Cameron Paul | Parkway North | 2015-2017 | | 86 | 12 |
| 12 | Grant Hollister | Blue Springs South | 2020-2023 | | 136 | 12 |
| 18 | Larry Cattoor | Hillsboro | 1988-1990 | | 62 | 11 |
| 18 | Danny Powers | Carl Junction | 1998-2001 | | 82 | 11 |
| 18 | Truman Marek | Bishop LeBlond | 2000-2003 | | 78 | 11 |
| 18 | Don Lambert | Westminster Christian Academy | 2005-2007 | | 85 | 11 |