| Rank | Student | School | Years | | G | 1B |
| 1 | Connor S Basler | Valle Catholic | 2012-2015 | | 116 | 142 |
| 2 | Chance Wolfe | Clever | 2010-2013 | | 111 | 131 |
| 3 | Tytus A Cissell | Francis Howell | 2020-2023 | | 158 | 125 |
| 4 | Cody Payne | Chaffee | 2010-2013 | | 107 | 122 |
| 5 | Spencer Sander | Saxony Lutheran | 2008-2011 | | 90 | 108 |
| 6 | Robert Mitchell | Herculaneum | 1998-2001 | | 105 | 103 |
| 7 | William Baker | Hillsboro | 1994-1997 | | 86 | 97 |
| 8 | David Kramer | Parkway North | 2000-2003 | | 103 | 94 |
| 8 | Blake DeWitt | Sikeston | 2001-2004 | | 107 | 94 |
| 10 | Josh Tebbe | Parkway North | 2000-2003 | | 95 | 93 |
| 10 | Andrew Teaster | Hollister | 2004-2006 | | 71 | 93 |
| 10 | Luke Tebbe | Walnut Grove | 2008-2011 | | 85 | 93 |
| 13 | Mike Hopkins | Francis Howell | 2002-2005 | | 114 | 91 |
| 14 | Chase Looney | Lafayette County | 2014-2017 | | 93 | 90 |
| 15 | Ben Turner | Westminster Christian Academy | 2005-2008 | | 109 | 88 |
| 15 | Ryan Allee | Westminster Christian Academy | 2009-2011 | | 93 | 88 |