| Rank | Student | School | Years | | G | Total |
| 1 | Tate Matheny | Westminster Christian Academy | 2009-2012 | | 111 | 191 |
| 2 | Spencer Greene | Mansfield | 2014-2017 | | 144 | 187 |
| 3 | Blake DeWitt | Sikeston | 2001-2004 | | 107 | 186 |
| 4 | Connor S Basler | Valle Catholic | 2012-2015 | | 116 | 182 |
| 5 | Chance Wolfe | Clever | 2010-2013 | | 111 | 175 |
| 6 | Nathan Geile | Valle Catholic | 2007-2010 | | 116 | 163 |
| 7 | Jake Whitesides | Hickman | 1997-2000 | | 100 | 161 |
| 8 | Robert Mitchell | Herculaneum | 1998-2001 | | 105 | 157 |
| 9 | Greg Rodgers | Francis Howell | 2000-2003 | | 113 | 156 |
| 10 | Chris Cornelius | Vianney | 2013-2016 | | 142 | 155 |
| 11 | Jeff Melton | Herculaneum | 2000-2003 | | 106 | 152 |
| 12 | Devin Fields | Green City | 2015-2018 | | 107 | 150 |
| 13 | Jacob Turner | Westminster Christian Academy | 2006-2009 | | 115 | 149 |
| 13 | Jake Welch | Bernie | 2007-2010 | | 94 | 149 |
| 15 | Ben Turner | Westminster Christian Academy | 2005-2008 | | 109 | 145 |
| 15 | Larry Schimsa | Pacific | 2006-2009 | | 86 | 145 |
| 17 | Hunter Dame | Conway | 2013-2016 | | 114 | 137 |
| 18 | Camden Williams | Green City | 2014-2017 | | 107 | 123 |
| 19 | Chase Krogman | Liberty (Wentzville) | 2016-2019 | | 106 | 120 |