| Rank | Student | Grade | School | Year | | PO | Ast | E | G | Pct |
| 1 | Reggie Schuh | Sr | Walnut Grove | 1995 | | 144 | 14 | 0 | 16 | 1.000 |
| 1 | Bill Sucharski | Sr | Hillsboro | 1996 | | 118 | 2 | 0 | 18 | 1.000 |
| 1 | Ben Turner | Jr | Westminster Christian Academy | 2007 | | 166 | 12 | 0 | 30 | 1.000 |
| 1 | Ben Turner | Sr | Westminster Christian Academy | 2008 | | 229 | 15 | 0 | 27 | 1.000 |
| 1 | Zac Williams | Sr | Conway | 2010 | | 216 | 25 | 0 | 30 | 1.000 |
| 1 | Kaleb Baker | Sr | Aurora | 2016 | | 285 | 57 | 0 | 31 | 1.000 |
| 7 | Ryan Lee Cline | So | Aurora | 2017 | | 348 | 0 | 1 | 32 | .997 |
| 8 | Baden Luke Hackworth | Sr | Jackson | 2022 | | 307 | 20 | 1 | 41 | .997 |
| 9 | Luke Tebbe | Fr | Walnut Grove | 2008 | | 188 | 8 | 1 | 21 | .995 |
| 10 | Nick Meinhardt | Jr | Springfield Catholic | 2003 | | 149 | 29 | 1 | 24 | .994 |
| 11 | Tony Kalna | Sr | Northwest (Cedar Hill) | 2007 | | 154 | 19 | 1 | 24 | .994 |
| 12 | Mason Eubanks | Jr | Kelly | 2021 | | 148 | 3 | 1 | 25 | .993 |
| 13 | Joe Fehlker | Sr | Hillsboro | 2001 | | 127 | 20 | 1 | 27 | .993 |
| 14 | Kevin Werntz | Sr | Northwest (Cedar Hill) | 2005 | | 102 | 12 | 1 | 26 | .991 |
| 15 | Casey Korn | Jr | Northwest (Cedar Hill) | 2004 | | 95 | 14 | 1 | 24 | .991 |
| 16 | Kaiden Cole Vanwinkle | Jr | Winona | 2020 | | 129 | 14 | 2 | 17 | .986 |
| 17 | Landon James Watkins | Sr | Jackson | 2022 | | 169 | 3 | 3 | 41 | .983 |
| 18 | Devin Fields | Jr | Green City | 2017 | | 152 | 14 | 3 | 19 | .982 |