| Rank | Student | Grade | School | Year | | G | Total |
| 1 | Jayden Hasam | So | University Academy Charter | 2021 | | 27 | 64 |
| 2 | Jared Alverson | Jr | Exeter | 2017 | | 23 | 58 |
| 3 | Cody Burkhardt | Sr | Hermitage | 2009 | | 21 | 56 |
| 4 | James Gowin | Sr | Hermitage | 2008 | | 24 | 55 |
| 5 | David Miller | Sr | Belle | 1983 | | 16 | 51 |
| 5 | Garyn Hall | Sr | Houston | 2022 | | 26 | 51 |
| 7 | Garrett Mork | So | Bismarck | 2021 | | 22 | 50 |
| 7 | Lucas Robert Efken | Sr | Bayless | 2022 | | 23 | 50 |
| 9 | Jayden Hasam | Fr | University Academy Charter | 2020 | | 19 | 49 |
| 10 | Jeff Morris | Sr | Diamond | 2006 | | 25 | 48 |
| 10 | Aaron Garner | Jr | Pierce City | 2018 | | 24 | 48 |
| 12 | Kimo Concepcion | Jr | Stoutland | 1999 | | 17 | 47 |
| 13 | Nick Moore | Sr | Wright City | 2022 | | 23 | 45 |
| 13 | Nick Moore | Sr | Wright City | 2022 | | 23 | 45 |
| 15 | Kimo Concepcion | So | Stoutland | 1998 | | 16 | 44 |
| 16 | Nathan Dunn | Sr | Marshfield | 2000 | | 29 | 42 |
| 16 | Danny Maier | Sr | New Franklin | 2004 | | 21 | 42 |
| 16 | Colin Gowin | So | Hermitage | 2010 | | 21 | 42 |
| 16 | Garrett Mork | Jr | Bismarck | 2022 | | 20 | 42 |
| 20 | Rick Huskey | Sr | Herculaneum | 1997 | | 25 | 40 |
| 20 | Ryan Smith | Sr | Hermitage | 2008 | | 24 | 40 |
| 20 | Garyn Hall | Jr | Houston | 2021 | | 23 | 40 |
| 23 | Ryker Zimmerman | Jr | Southern Boone | 2022 | | 35 | 38 |
| 24 | Kaden Matthew Kinsler | So | Elsberry | 2020 | | 25 | 37 |
| 25 | Kaden Matthew Kinsler | Jr | Elsberry | 2021 | | 30 | 35 |
| 26 | Garyn Hall | So | Houston | 2020 | | 20 | 33 |
| 27 | Connor Earleywine | Jr | Jefferson City | 2020 | | 37 | 29 |
| 28 | Tyler Lutjen | Sr | Clinton | 2020 | | 26 | 28 |
| 29 | Danny Lee Venable | Sr | Houston | 2022 | | 26 | 24 |
| 30 | Gavin Jansen | Sr | Kelly | 2020 | | 28 | 23 |
| 30 | Gavin Jansen | Sr | Kelly | 2021 | | 25 | 23 |
| 32 | Aiden Kelly | Jr | Houston | 2022 | | 25 | 22 |
| 33 | | Jr | Clinton | 2016 | | 22 | 21 |
| 33 | Trey Miller | Jr | Clinton | 2016 | | 22 | 21 |
| 35 | Zachary Kent Craig | Sr | Summersville | 2021 | | 14 | 20 |
| 36 | Zeke Jones | Jr | Summersville | 2022 | | 19 | 18 |
| 37 | Crockett Parham | Sr | Summersville | 2018 | | 17 | 16 |