| Rank | Student | Grade | School | Year | | 3B | G | PerG |
| 1 | Mark Williams | Jr | Cardinal Ritter | 2005 | | 9 | 17 | .529 |
| 2 | Nick Andriano | Jr | Mid-Buchanan | 2010 | | 10 | 20 | .500 |
| 3 | Jess Davis | Sr | Kearney | 2016 | | 13 | 29 | .448 |
| 4 | Brian Rothermich | Sr | St. Dominic | 1976 | | 9 | 21 | .429 |
| 5 | Tyler Ketterman | Jr | Nevada | 2015 | | 10 | 26 | .385 |
| 6 | Konner Hatfield | Sr | Hollister | 2020 | | 12 | 32 | .375 |
| 7 | Nicholas Andrew Shields | Jr | Bayless | 2018 | | 8 | 22 | .364 |
| 8 | Mickey Wallace | Sr | Ritenour | 2004 | | 10 | 28 | .357 |
| 9 | Evan Jones | Sr | Mansfield | 2006 | | 7 | 20 | .350 |
| 10 | Brock Bond | Sr | Lindbergh | 2004 | | 8 | 23 | .348 |
| 11 | Nick Wilfong | Jr | Francis Howell | 1996 | | 9 | 26 | .346 |
| 11 | Ryan Morgan | Sr | St. Louis University | 2005 | | 9 | 26 | .346 |
| 13 | Tate Matheny | Sr | Westminster Christian Academy | 2012 | | 11 | 32 | .344 |
| 14 | Jairus Byrd | Sr | Clayton | 2005 | | 9 | 27 | .333 |
| 15 | Kevin Addington | Sr | Nevada | 1992 | | 7 | 22 | .318 |
| 15 | Dan Walsh | Sr | Brentwood | 2004 | | 7 | 22 | .318 |
| 17 | Landon Richards | Sr | Hollister | 2020 | | 8 | 32 | .250 |
| 18 | Brett Norfleet | Jr | Francis Howell | 2021 | | 8 | 42 | .190 |