| Rank | Student | School | Opponent | Date | | Inn | Total |
| 1 | Tim Mullen | Steelville | Newburg | 4/7/1998 | | 7 | 3 |
| 1 | Ray Dale Sturgis Jr | Holden | Sherwood | 4/1/1999 | | 3 | 3 |
| 1 | Clinton Irwin | Hume | Bronaugh | 9/20/2007 | | 1 | 3 |
| 1 | Andy Yarick | Hume | Bronaugh | 9/20/2007 | | 1 | 3 |
| 1 | Tony Schulte | St. Dominic | Notre Dame (Cape Girardeau) | 5/30/2008 | at Springfield | 6 | 3 |
| 1 | Will Mulligan | St. Dominic | Notre Dame (Cape Girardeau) | 5/30/2008 | at Springfield | 6 | 3 |
| 1 | Ryan Cooper | Owensville | Belle | 3/31/2009 | | 1 | 3 |
| 1 | John Hull | Plattsburg | Lutheran (Kansas City) | 4/11/2018 | | 2 | 3 |
| 1 | Asa L Wilson | Nevada | Neosho | 5/7/2022 | | 6 | 3 |