| Rank | Student | School | Year | | R | G | PerG |
| 1 | | La Plata | 2010 | | 276 | 20 | 13.800 |
| 2 | | Mansfield | 1990 | | 260 | 20 | 13.000 |
| 3 | | La Plata | 2009 | | 201 | 16 | 12.563 |
| 4 | | Lakeland | 1998 | | 271 | 22 | 12.318 |
| 5 | | Bishop LeBlond | 2000 | | 275 | 23 | 11.957 |
| 6 | | Licking | 2013 | | 245 | 21 | 11.667 |
| 7 | | Steelville | 1997 | | 232 | 20 | 11.600 |
| 8 | | Mansfield | 1999 | | 285 | 25 | 11.400 |
| 8 | | Santa Fe | 2011 | | 228 | 20 | 11.400 |
| 10 | | Hermitage | 2008 | | 284 | 25 | 11.360 |
| 11 | | Summit Christian Academy | 2012 | | 327 | 29 | 11.276 |
| 12 | | Westminster Christian Academy | 2017 | | 359 | 32 | 11.219 |
| 13 | | Santa Fe | 2009 | | 211 | 19 | 11.105 |
| 14 | | Valle Catholic | 2020 | | 357 | 33 | 10.818 |
| 15 | | Valley Park | 2017 | | 332 | 31 | 10.710 |
| 16 | | Marion C. Early | 2020 | | 280 | 28 | 10.000 |
| 16 | | Marion C. Early | 2020 | | 280 | 28 | 10.000 |
| 18 | | Valle Catholic | 2013 | | 323 | 34 | 9.500 |
| 19 | | Webb City | 2020 | | 302 | 32 | 9.438 |
| 20 | | Portageville | 2022 | | 357 | 38 | 9.395 |
| 21 | | Salisbury | 2024 | | 214 | 23 | 9.304 |
| 22 | | Valle Catholic | 2022 | | 307 | 34 | 9.029 |
| 23 | | Portageville | 2023 | | 335 | 38 | 8.816 |
| 24 | | Scott City | 2023 | | 290 | 33 | 8.788 |
| 25 | | Valle Catholic | 2015 | | 313 | 36 | 8.694 |
| 26 | | Jackson | 2022 | | 355 | 41 | 8.659 |
| 27 | | Valle Catholic | 2014 | | 298 | 35 | 8.514 |
| 28 | | Clinton | 2013 | | 230 | 28 | 8.214 |
| 29 | | Plattsburg | 2021 | | 311 | 38 | 8.184 |
| 30 | | Southern Boone | 2021 | | 269 | 36 | 7.472 |
| 31 | | Southern Boone | 2022 | | 259 | 35 | 7.400 |
| 32 | | Francis Howell | 2021 | | 298 | 42 | 7.095 |