| Rank | Student | School | Year | | 2B | G | PerG |
| 1 | | Northwest (Hughesville) | 2000 | | 70 | 23 | 3.043 |
| 2 | | Westminster Christian Academy | 2006 | | 82 | 28 | 2.929 |
| 3 | | Herculaneum | 2001 | | 83 | 29 | 2.862 |
| 4 | | Mansfield | 1999 | | 71 | 25 | 2.840 |
| 5 | | Westminster Christian Academy | 2007 | | 84 | 30 | 2.800 |
| 6 | | Lakeland | 2002 | | 66 | 24 | 2.750 |
| 7 | | Hickman | 2005 | | 82 | 30 | 2.733 |
| 8 | | Mansfield | 2000 | | 80 | 30 | 2.667 |
| 9 | | Westminster Christian Academy | 2017 | | 84 | 32 | 2.625 |
| 10 | | Bishop LeBlond | 2000 | | 59 | 23 | 2.565 |
| 11 | | Iberia | 2018 | | 51 | 20 | 2.550 |
| 12 | | Kelly | 2020 | | 65 | 28 | 2.321 |
| 13 | | Ft. Zumwalt West | 2014 | | 75 | 33 | 2.273 |
| 14 | | Webb City | 2020 | | 65 | 32 | 2.031 |
| 15 | | Webb City | 2024 | | 65 | 34 | 1.912 |
| 16 | | Hollister | 2020 | | 58 | 32 | 1.813 |
| 17 | | Jackson | 2022 | | 74 | 41 | 1.805 |
| 18 | | Tipton | 2023 | | 52 | 30 | 1.733 |
| 19 | | Francis Howell | 2021 | | 68 | 42 | 1.619 |
| 20 | | Jackson | 2024 | | 59 | 38 | 1.553 |