| Rank | Student | School | Opponent | Date | | Inn | R |
| 1 | | Van Buren | Eminence | 5/5/2011 | | 2 | 32 |
| 2 | | Barstow | | 5/9/2018 | | 1 | 31 |
| 3 | | East Prairie | Scott County Central | 5/5/2006 | | 2 | 24 |
| 4 | | New Franklin | Prairie Home | 4/4/2016 | | 2 | 22 |
| 5 | | Licking | Summersville | 4/22/2013 | | 2 | 21 |
| 5 | | Plattsburg | Lutheran (Kansas City) | 4/11/2018 | | 2 | 21 |
| 7 | | Skyline | Walnut Grove | 3/25/2000 | | 1 | 20 |
| 8 | | St. Dominic | Notre Dame (Cape Girardeau) | 5/30/2008 | at Springfield | 6 | 19 |
| 8 | | St. Dominic | Notre Dame (Cape Girardeau) | 5/30/2008 | | 6 | 19 |
| 10 | | Owensville | Belle | 3/31/2009 | | 1 | 18 |
| 11 | | Mansfield | Niangua | 4/8/1994 | | 1 | 17 |
| 11 | | Fordland | Niangua | 4/24/2007 | | 5 | 17 |
| 11 | | Sarcoxie | Sarcoxie | 4/25/2023 | | 6 | 17 |
| 11 | | Sarcoxie | Bronaugh | 4/25/2023 | | 6 | 17 |
| 15 | | Beaumont | St. Peter's (Joplin) | 5/25/1950 | | 5 | 16 |
| 15 | | Kirkwood | Shelbina | 5/24/1955 | at St. Louis | 4 | 16 |
| 15 | | Halfway | Walnut Grove | 3/21/2000 | at St. Louis | 1 | 16 |
| 15 | | McDonald County | Central (Springfield) | 4/3/2001 | | 4 | 16 |
| 19 | | Sarcoxie | Sarcoxie | 4/25/2023 | | 2 | 15 |
| 19 | | Sarcoxie | Bronaugh | 4/25/2023 | | 2 | 15 |
| 21 | | Smithville | Ozark | 5/26/1979 | | 1 | 13 |
| 22 | | St. Francis Borgia | Sherwood | 5/23/1975 | | 2 | 12 |
| 23 | | Lindbergh | Neosho | 5/22/1981 | | 6 | 10 |
| 23 | | Platte County | St. Mary's (Independence) | 6/1/2002 | | 1 | 10 |
| 23 | | New Bloomfield | Summit Christian Academy | 6/2/2011 | | 7 | 10 |