| Rank | School | Opponent | Date | | Inn | Total |
| 1 | College Heights Christian | Sarcoxie | 3/19/2008 | at Diamond | | 20 |
| 1 | Macks Creek | | 4/13/2010 | | 7 | 20 |
| 3 | Hermitage | Halfway | 4/30/2008 | | | 18 |
| 3 | Northwestern (Mendon) | Southwest (Livingston County) | 5/1/2008 | | | 18 |
| 5 | Central (Cape Girardeau) | Immanuel Lutheran Jr. | 5/4/1960 | | | 17 |
| 5 | Walnut Grove | Hermitage | 4/6/2010 | at Wheatland | | 17 |
| 5 | Fatima | Hallsville | 5/30/2013 | | | 17 |
| 5 | Fatima | Hallsville | 5/30/2013 | | 7 | 17 |
| 5 | New Franklin | Prairie Home | 4/4/2016 | | | 17 |
| 5 | Plattsburg | Stewartsville | 3/17/2023 | | 6 | 17 |
| 11 | Ritenour | Normandy Collaborative | 4/1/1997 | | 5 | 16 |
| 11 | Steelville | Laquey | 5/10/1999 | | | 16 |
| 11 | Sarcoxie | College Heights Christian | 3/19/2008 | at Diamond | | 16 |
| 11 | Harrisburg | | 4/23/2018 | Pilot Grove | 13 | 16 |
| 11 | Plattsburg | Rock Port | 5/5/2022 | | 5 | 16 |
| 16 | Iberia | Mansfield | 6/1/2005 | | 7 | 13 |
| 17 | New Bloomfield | Southland | 6/1/1989 | | 7 | 12 |
| 18 | Dixon | Chaffee | 5/28/1977 | | 7 | 11 |
| 18 | Joplin | Oak Park | 5/27/1983 | | 7 | 11 |
| 18 | Hillcrest | Central (Cape Girardeau) | 6/3/1988 | | 7 | 11 |
| 18 | Pilot Grove | Southland | 5/31/1989 | | 7 | 11 |
| 18 | Truman | Christian Brothers College | 6/2/1990 | | 7 | 11 |
| 18 | Christian Brothers College | Central (Cape Girardeau) | 6/1/1991 | | 7 | 11 |
| 18 | St. Elizabeth | North Pemiscot | 6/1/1995 | | 7 | 11 |
| 18 | Marion C. Early | New Haven | 5/30/2002 | | 7 | 11 |
| 18 | St. Dominic | Notre Dame (Cape Girardeau) | 5/30/2008 | | 5 | 11 |
| 18 | Savannah | Lutheran South | 6/1/2012 | | 7 | 11 |
| 18 | Southern Boone | Southern Boone | 6/1/2022 | vs. Marshall | 11 | 11 |
| 18 | Southern Boone | Marshall | 6/1/2022 | vs. Marshall | 11 | 11 |