| Rank | Student | School | Opponent | Date | | Inn | W |
| 1 | | Sparta | Sparta | 9/13/2024 | | 7 | 21 |
| 2 | | College Heights Christian | Sarcoxie | 3/19/2008 | at Diamond | | 20 |
| 2 | | Macks Creek | | 4/13/2010 | | 7 | 20 |
| 4 | | Hermitage | Halfway | 4/30/2008 | | | 18 |
| 4 | | Northwestern (Mendon) | Southwest (Livingston County) | 5/1/2008 | | | 18 |
| 6 | | Central (Cape Girardeau) | Immanuel Lutheran Jr. | 5/4/1960 | | | 17 |
| 6 | | Walnut Grove | Hermitage | 4/6/2010 | at Wheatland | | 17 |
| 6 | | Fatima | Hallsville | 5/30/2013 | | | 17 |
| 6 | | Fatima | Hallsville | 5/30/2013 | | 7 | 17 |
| 6 | | New Franklin | Prairie Home | 4/4/2016 | | | 17 |
| 6 | | Plattsburg | Stewartsville | 3/17/2023 | | 6 | 17 |
| 12 | | Ritenour | Normandy Collaborative | 4/1/1997 | | 5 | 16 |
| 12 | | Steelville | Laquey | 5/10/1999 | | | 16 |
| 12 | | Sarcoxie | College Heights Christian | 3/19/2008 | at Diamond | | 16 |
| 12 | | Harrisburg | | 4/23/2018 | Pilot Grove | 13 | 16 |
| 12 | | Plattsburg | Rock Port | 5/5/2022 | | 5 | 16 |
| 17 | | Iberia | Mansfield | 6/1/2005 | | 7 | 13 |
| 17 | | Osceola | Fair Play | 5/12/2025 | | 4 | 13 |
| 19 | | New Bloomfield | Southland | 6/1/1989 | | 7 | 12 |
| 19 | | Osceola | Humansville | 5/13/2025 | | 7 | 12 |
| 21 | | Dixon | Chaffee | 5/28/1977 | | 7 | 11 |
| 21 | | Joplin | Oak Park | 5/27/1983 | | 7 | 11 |
| 21 | | Hillcrest | Central (Cape Girardeau) | 6/3/1988 | | 7 | 11 |
| 21 | | Pilot Grove | Southland | 5/31/1989 | | 7 | 11 |
| 21 | | Truman | Christian Brothers College | 6/2/1990 | | 7 | 11 |
| 21 | | Christian Brothers College | Central (Cape Girardeau) | 6/1/1991 | | 7 | 11 |
| 21 | | St. Elizabeth | North Pemiscot | 6/1/1995 | | 7 | 11 |
| 21 | | Marion C. Early | New Haven | 5/30/2002 | | 7 | 11 |
| 21 | | St. Dominic | Notre Dame (Cape Girardeau) | 5/30/2008 | | 5 | 11 |
| 21 | | Savannah | Lutheran South | 6/1/2012 | | 7 | 11 |
| 21 | | Southern Boone | Southern Boone | 6/1/2022 | vs. Marshall | 11 | 11 |
| 21 | | Southern Boone | Marshall | 6/1/2022 | vs. Marshall | 11 | 11 |