| Rank | School | Opponent | Date | | Inn | Total |
| 1 | Beaumont | St. Peter's (Joplin) | 5/25/1950 | at St. Louis | 5 | 33 |
| 1 | Central (Park Hills) | West County | 4/26/1994 | | | 33 |
| 3 | Licking | Summersville | 4/22/2013 | | | 31 |
| 4 | Central (Cape Girardeau) | Notre Dame (Cape Girardeau) | 4/8/1960 | | | 28 |
| 4 | Bishop LeBlond | East Buchanan | 5/13/2000 | | | 28 |
| 6 | Mansfield | Seymour | 4/9/1990 | | | 26 |
| 6 | Lawson | North Platte | 4/1/2003 | | 5 | 26 |
| 8 | Willard | Mt. Vernon | 4/14/2000 | | 5 | 25 |
| 8 | New Bloomfield | Summit Christian Academy | 6/2/2011 | Class 2 Final | | 25 |
| 8 | New Bloomfield | Summit Christian Academy | 6/2/2011 | | 7 | 25 |
| 11 | Stoutland | Laquey | 8/31/1998 | | | 24 |
| 11 | Holden | Sherwood | 4/1/1999 | | | 24 |
| 11 | Skyline | Walnut Grove | 3/25/2000 | | | 24 |
| 11 | Mansfield | Niangua | 5/3/2000 | | 5 | 24 |
| 11 | Monett | Purdy | 4/1/2003 | | 5 | 24 |
| 16 | Parkway North | | 5/3/1999 | | 5 | 22 |
| 17 | Conway | Stockton | 6/3/2010 | | 7 | 19 |
| 17 | Valle Catholic | Canton | 6/1/2016 | | 7 | 19 |