| Rank | School | Opponent | Date | | Inn | PA |
| 1 | East Prairie | Scott County Central | 5/5/2006 | | 2 | 30 |
| 2 | Plattsburg | Lutheran (Kansas City) | 4/11/2018 | | 2 | 26 |
| 3 | Plattsburg | Tina-Avalon | 3/25/2026 | | 2 | 24 |
| 4 | St. Dominic | Notre Dame (Cape Girardeau) | 5/30/2008 | at Springfield | 6 | 23 |
| 4 | Owensville | Belle | 3/31/2009 | | 1 | 23 |
| 6 | Lafayette (Wildwood) | Eureka | 4/15/2016 | | 0 | 22 |
| 7 | Tipton | Otterville | 3/26/2019 | | 1 | 21 |
| 7 | Plattsburg | Stewartsville | 3/19/2026 | | 2 | 21 |
| 9 | Nevada | Neosho | 5/7/2022 | | 6 | 20 |
| 10 | Steelville | Newburg | 4/7/1998 | | 7 | 19 |
| 10 | Monett | Purdy | 4/1/2003 | | 2 | 19 |
| 10 | Northwest (Cedar Hill) | Webster Groves | 4/12/2010 | | 3 | 19 |
| 10 | Eugene | Tuscumbia | 5/6/2011 | | 1 | 19 |
| 10 | Holt | Ft. Zumwalt East | 4/5/2011 | | 2 | 19 |
| 15 | Greenville | East Carter | 4/2/2002 | | 2 | 18 |
| 15 | Lawson | Lathrop | 3/29/2006 | | 2 | 18 |
| 15 | Lawson | North Platte | 4/19/2007 | | 1 | 18 |
| 18 | Neelyville | Neelyville | 5/10/2022 | | 7 | 5 |