| Rank | Student | School | Years | | G | HBP |
| 1 | Tucker Dement | Ellington | 2018-2021 | | 135 | 58 |
| 2 | Jacob Talbot | Plato | 2004-2006 | | 67 | 45 |
| 2 | Justin Perkins | Francis Howell | 2013-2016 | | 75 | 45 |
| 4 | Bricker Berry | Macks Creek | 2009-2013 | | 68 | 40 |
| 5 | Wyatt Francis Moran | Plattsburg | 2020-2022 | | 93 | 39 |
| 6 | Jared Gage | Summit Christian Academy | 2009-2012 | | | 38 |
| 7 | Brett Gollhofer | Monett | 2013-2016 | | 82 | 36 |
| 7 | Carter Karotka | Southern Boone | 2018-2021 | | 88 | 36 |
| 9 | Colton McAnally | Grandview (Hillsboro) | 2015-2018 | | 69 | 35 |
| 10 | Cody Burkhardt | Hermitage | 2006-2009 | | 85 | 33 |
| 11 | Brent Maggard | Sparta | 2002-2005 | | 128 | 32 |
| 12 | Kyle McCallister | Monett | 2012-2015 | | 100 | 30 |
| 12 | Jesse Linton | Macks Creek | 2013-2017 | | 81 | 30 |
| 14 | Craig Penley | Plato | 2002-2005 | | 82 | 28 |
| 15 | Justin Jackson | Hickman | 2003-2005 | | 69 | 25 |
| 16 | LIndell Ray Harmon | Southern Boone | 2003-2006 | | 56 | 22 |
| 17 | Jesse Auten | Lakeland | 1999-20002 | | 93 | 21 |
| 18 | Andy Oliver | Fatima | 1994-1997 | | 70 | 20 |
| 18 | John Watson | Christian Brothers College | 2000-2002 | | 80 | 20 |
| 18 | Kris Irwin | Plato | 2002-2005 | | 82 | 20 |
| 18 | Mike Macke | Ft. Zumwalt South | 2007-2009 | | 69 | 20 |
| 18 | Ronnie Ray | Clearwater | 2007-2010 | | 75 | 20 |