| Rank | 3B | Student | School | Opponent | Date | |
| 1 | 3 | Kelsey Biggs | Seckman | Parkway North | 9/6/2006 | |
| 1 | 3 | Kelsey Mitchell | Lutheran South | Rock Bridge | 9/8/2006 | |
| 1 | 3 | Hana Bolen | Jackson | Fox | 9/22/2007 | |
| 1 | 3 | Lauren Reinagel | Notre Dame (Cape Girardeau) | Poplar Bluff | 9/4/2007 | |
| 1 | 3 | Courtney Coleman | Sarcoxie | Crane | 8/25/2009 | |
| 1 | 3 | Kelli Koehler | Weaubleau | Halfway | 9/20/2010 | |
| 1 | 3 | Alexis Van Nostrand | Palmyra | Hannibal | 10/4/2011 | |
| 1 | 3 | Kylie R. Swinney | St. Charles | McCluer | 8/29/2016 | |
| 1 | 3 | Jacque Gentzell | Lathrop | | 9/6/2016 | |
| 1 | 3 | Sarah Handrahan | Jefferson (Festus) | Bayless | 9/7/2016 | |
| 1 | 3 | Anna Besand | Perryville | | 9/11/2017 | |
| 12 | 2 | Alaney Moore | Kelly | Twin Rivers | 9/22/2020 | |
| 12 | 2 | Hailey Jo Lemunyon | Maysville | La Plata | 10/30/2021 | |
| 12 | 2 | Karoline Klebba | Helias Catholic | Kearney | 10/28/2022 | |
| 12 | 2 | Chloe Edwards | Iberia | Laquey | 9/27/2024 | |
| 16 | 1 | Devon Francy | Pleasant Hill | | 1/1/2001 | Class 3 |
| 16 | 1 | Kristin Nottelmann | Rockwood Summit | | 1/1/2006 | Class 4 |
| 16 | 1 | Catlin Evans | Pleasant Hope | | 1/1/2011 | Class 2 |
| 16 | 1 | Shayla Jansson | Kennett | Crest Ridge | 1/1/2014 | |
| 16 | 1 | Summer Shockley | Van Buren | | 1/1/2016 | Class 1 |
| 16 | 1 | Genesis Smith | Lincoln | Kennett | 1/1/2019 | |
| 16 | 1 | Haley Mackey | Lincoln | Kennett | 1/1/2019 | |
| 16 | 1 | Livia Dunn | Jasper | Wellington-Napoleon | 1/1/2022 | |
| 16 | 1 | Ayden Shannon | Wellington-Napoleon | Jasper | 1/1/2022 | |
| 16 | 1 | Bree Shannon | Wellington-Napoleon | Jasper | 1/1/2022 | |
| 16 | 1 | Cheyanne Bieber | Mt. Vernon | West County | 1/1/2023 | |
| 16 | 1 | Morgan Simily | West County | Mt. Vernon | 1/1/2023 | |
| 16 | 1 | Kiya Inman | Concordia | Ash Grove | 5/21/2024 | |
| 16 | 1 | Hadley Wilson | Kennett | Diamond | 5/21/2024 | |