| Rank | Student | School | Years | | G | G |
| 1 | Valerie Teter | Bevier | 2003-2006 | | 97 | 25 |
| 2 | Dana Halstead | La Plata | 1998-2001 | | 98 | 20 |
| 2 | Kenya Fuemmeler | Salisbury | 1999-2002 | | 88 | 20 |
| 2 | Taylor Baxter | Palmyra | 2006-2009 | | 97 | 20 |
| 5 | Lauren Delaney | Helias Catholic | 2002-2005 | | 93 | 17 |
| 5 | Bethany Collard | Harrisburg | 2003-2006 | | 85 | 17 |
| 5 | Lauren Reinagel | Notre Dame (Cape Girardeau) | 2006-2009 | | 88 | 17 |
| 8 | Heather Feltmann | Cor Jesu Academy | 1987-1989 | | 35 | 13 |
| 8 | Megan Nikolenko | Linn | 1997-1999 | | 75 | 13 |
| 8 | Katie Shockley | Crocker | 2007-2010 | | 66 | 13 |
| 8 | Hannah Harman | Walnut Grove | 2007-2010 | | 104 | 13 |
| 12 | Maddy Colin | College Heights Christian | 2020-2023 | | 83 | 12 |
| 13 | Maddy Colin | College Heights Christian | 2020-2023 | | 83 | 6 |