| Rank | Student | School | Years | | G | R |
| 1 | Maleigh Elizabeth Lemings | Holcomb | 2020-2023 | | 127 | 243 |
| 2 | Paige Eddington | Doniphan | 2014-2017 | | 134 | 225 |
| 3 | Madison Marie Uptegrove | Father Tolton Regional Catholic | 2020-2023 | | 131 | 188 |
| 4 | Payge Evans | Mt. Vernon | 2020-2023 | | 128 | 175 |
| 5 | Emily Crane | Troy Buchanan | 2008-2011 | | 118 | 168 |
| 6 | Sammey Clara Bunch | Fatima | 2012-2015 | | 108 | 167 |
| 7 | Regan Nash | North Platte | 2011-2014 | | 94 | 164 |
| 8 | Cali Coombs | Russellville | 2019-2022 | | 115 | 163 |
| 9 | Sarah Roth | Northwest (Cedar Hill) | 2017-2020 | | 113 | 160 |
| 9 | Hailey Presley | Marion C. Early | 2020-2023 | | 123 | 160 |
| 11 | Karsyn Brooke | Mansfield | 2015-2018 | | 132 | 159 |
| 12 | Maddison Brown | Mt. Vernon | 2013-2016 | | 100 | 158 |
| 12 | Livia Dumm | Jasper | 2021-2023 | | 114 | 158 |
| 14 | Ragan Blinzler | Pierce City | 2014-2017 | | 99 | 156 |
| 14 | Lauren Taylor | Marion C. Early | 2019-2022 | | 96 | 156 |
| 16 | Zoe Brittan | Valley Park | 2004-2006 | | 74 | 154 |
| 17 | Bailey Burns | Puxico | 2015-2018 | | 80 | 153 |
| 18 | Tabitha Francka | Marion C. Early | 2012-2015 | | 95 | 152 |
| 19 | Kloee Williamson | McAuley Catholic | 2020-2023 | | 88 | 151 |
| 20 | Sydney Miller | Willow Springs | 2015-2018 | | 105 | 150 |
| 20 | Sophia Luetticke | Chillicothe | 2018-2021 | | 94 | 150 |
| 22 | Olivia Jo Pfeifer | Hannibal | 2014-2017 | | 95 | 148 |
| 23 | Valerie Teter | Bevier | 2003-2006 | | 99 | 146 |
| 24 | Alane Cordray | Mt. Vernon | 2014-2017 | | 84 | 144 |
| 25 | Kelli Koehler | Weaubleau | 2009-2012 | | 109 | 143 |
| 26 | Alexis Van Nostrand | Palmyra | 2009-2012 | | 124 | 141 |
| 26 | Kassidy Watts | Sparta | 2015-2018 | | 66 | 141 |
| 26 | Alexi Sanchez | Northwest (Cedar Hill) | 2018-2021 | | 106 | 141 |
| 26 | Maris Ollison | Versailles | 2018-2021 | | 103 | 141 |
| 30 | Abigail Rickermann | Festus | 2016-2019 | | 102 | 138 |
| 31 | Halle Gooch | Clearwater | 2014-2017 | | 93 | 133 |
| 32 | Audrey Glenski | North Platte | 2011-2014 | | 103 | 132 |
| 33 | Jonette Dixon | Putnam County | 1988-1991 | | 91 | 127 |
| 34 | Elle Smith | Blue Springs South | 2018-2021 | | 35 | 120 |
| 35 | Abigail King | Christian | 2014-2017 | | 84 | 116 |
| 36 | Maggie Painter | Marion C. Early | 2020-2023 | | 118 | 114 |