| Rank | Student | Grade | School | Year | | W | L | Total |
| 1 | Kelsey Kessler | Fr | Blue Springs | 2008 | | 31 | 0 | 100.0% |
| 1 | Kenya Fuemmeler | Sr | Salisbury | 2002 | | 26 | 0 | 100.0% |
| 1 | Madison McKinney | Sr | Norborne | 2015 | | 26 | 0 | 100.0% |
| 1 | Lauren Delaney | Sr | Helias Catholic | 2005 | | 25 | 0 | 100.0% |
| 1 | Jayne Miller | Jr | Palmyra | 1997 | | 24 | 0 | 100.0% |
| 1 | Jodi Schultz | Jr | Highland | 2005 | | 24 | 0 | 100.0% |
| 1 | Samantha Fleeman | Sr | Pleasant Hill | 2001 | | 22 | 0 | 100.0% |
| 1 | Kristin Nottelmann | Jr | Rockwood Summit | 2006 | | 22 | 0 | 100.0% |
| 1 | Lauren Delaney | So | Helias Catholic | 2003 | | 20 | 0 | 100.0% |
| 1 | Mariah A Wiskur | Fr | Northwest (Hughesville) | 2007 | | 16 | 0 | 100.0% |
| 1 | Annah Elise Junge | So | Marquette | 2016 | | 16 | 0 | 100.0% |
| 12 | Megan Daniels | Sr | Liberty | 2004 | | 28 | 1 | 96.6% |
| 12 | Lauren Reinagel | So | Notre Dame (Cape Girardeau) | 2007 | | 28 | 1 | 96.6% |
| 14 | Brooke Huitt | Jr | Lathrop | 2017 | | 26 | 1 | 96.3% |