| Rank | Student | Grade | School | Year | | G | Total |
| 1 | Stafanie Standley | Jr | Lamar | 2000 | | 24 | 65 |
| 2 | Chelsea King | Sr | Strafford | 2006 | | 28 | 56 |
| 2 | Molly Seabaugh | Jr | Advance | 2008 | | 16 | 56 |
| 2 | Bailey Burns | So | Puxico | 2016 | | 22 | 56 |
| 5 | Stefanie Standley | Sr | Lamar | 2001 | | 25 | 54 |
| 6 | Marissa Lewis | Sr | Metro | 2006 | | 26 | 52 |
| 6 | Bailey Burns | Fr | Puxico | 2015 | | 21 | 52 |
| 8 | Susan Reed | Sr | Eldon | 2001 | | 22 | 51 |
| 8 | Kelli Koehler | Sr | Weaubleau | 2002 | | 24 | 51 |
| 8 | Katy Roweton | Jr | Bolivar | 2007 | | 27 | 51 |
| 8 | Bailey Burns | Sr | Puxico | 2018 | | 21 | 51 |
| 12 | Julie Silver | Sr | Parkway Central | 2005 | | 26 | 49 |
| 13 | Christen Belcher | Jr | Notre Dame de Sion | 2002 | | 26 | 48 |
| 13 | Sydney Miller | Sr | Willow Springs | 2018 | | 26 | 48 |
| 15 | Mykaela Arellanes | Jr | Holt | 2013 | | 28 | 47 |
| 15 | Katelin Ann Kurima | Sr | Monett | 2017 | | 32 | 47 |
| 17 | Abigail Posten | So | Crocker | 2017 | | 26 | 44 |
| 18 | Ragan Blinzler | Sr | Pierce City | 2017 | | 25 | 43 |
| 19 | Kenna Wise | Jr | Clever | 2020 | | 24 | 42 |
| 20 | Abigail Rickermann | Sr | Festus | 2019 | | 29 | 41 |
| 21 | Katie Shuffler | So | Malden | 2018 | | 26 | 40 |
| 21 | Piper Schoemehl | Jr | Bernie | 2020 | | 24 | 40 |
| 23 | Olivia Jo Pfeifer | Sr | Hannibal | 2017 | | 21 | 39 |
| 23 | Abigail Rickermann | So | Festus | 2017 | | 27 | 39 |
| 25 | Kaesha George | Jr | Monett | 2018 | | 32 | 38 |
| 26 | Carissa Jean Martin | Jr | DeKalb | 2020 | | 16 | 37 |
| 27 | Macie Rae Fisher | So | Canton | 2021 | | 24 | 35 |
| 28 | Kelby Robinson | Jr | Holt | 2018 | | 28 | 34 |
| 29 | McKenna McCoy | Sr | Sullivan | 2016 | | 33 | 33 |
| 30 | McKenna McCoy | Jr | Sullivan | 2015 | | 29 | 32 |
| 30 | Bailey Burns | Jr | Puxico | 2017 | | 16 | 32 |
| 30 | Reagan Grace Thomure | So | Sullivan | 2018 | | 33 | 32 |
| 33 | Kelby Robinson | Sr | Holt | 2019 | | 29 | 31 |
| 33 | Elle Smith | Sr | Blue Springs South | 2021 | | 35 | 31 |
| 35 | Peyton Corrigan | Sr | Holden | 2018 | | 32 | 30 |
| 35 | Jayli Johnson | Jr | College Heights Christian | 2021 | | 23 | 30 |
| 37 | Alexa Higgins | Sr | Brashear | 2019 | | 20 | 29 |
| 38 | Mykaela Arellanes | Sr | Holt | 2014 | | 32 | 28 |
| 38 | Magdalene Dooley | Jr | Christian | 2017 | | 22 | 28 |
| 38 | Kloee Williamson | So | McAuley Catholic | 2021 | | 23 | 28 |
| 38 | Kaetlyn Danley | So | Holcomb | 2021 | | 33 | 28 |
| 42 | Lilly Jones | Sr | Kelly | 2018 | | 24 | 26 |
| 42 | Sophia Luetticke | Jr | Chillicothe | 2020 | | 22 | 26 |
| 42 | Sophia Luetticke | Sr | Chillicothe | 2021 | | 35 | 26 |
| 45 | Kinsey J Fiedler | Sr | Lee's Summit North | 2020 | | 32 | 25 |
| 46 | Sierra Janette Snyder | So | Brashear | 2019 | | 20 | 24 |
| 47 | Maleigh Lemings | So | Holcomb | 2021 | | 33 | 20 |