| Rank | Student | Grade | School | Year | | G | Total |
| 1 | Madison McKinney | Sr | Norborne | 2015 | | 29 | 66 |
| 2 | Bailee Bryant | Sr | Holden | 2018 | | 32 | 63 |
| 3 | Julia Higgins | Sr | Republic | 2018 | | 28 | 60 |
| 4 | Morgan Loggins | Sr | Waynesville | 2017 | | 29 | 59 |
| 4 | Emerson Bates | Jr | Wellington-Napoleon | 2018 | | 25 | 59 |
| 4 | Madison White | Sr | Rock Bridge | 2019 | | 35 | 59 |
| 7 | Brianna Isabelle Lore | Jr | Sullivan | 2010 | | 27 | 58 |
| 8 | Kari Hillenburg | Sr | Pleasant Hope | 2012 | | 30 | 56 |
| 8 | Camryn Pryor | Jr | Salem | 2015 | | 28 | 56 |
| 8 | Ashley Ellis | Sr | Fox | 2015 | | 32 | 56 |
| 11 | Kirstain Burger | Sr | Notre Dame (Cape Girardeau) | 2006 | | 27 | 55 |
| 11 | Carlie Anne Rose | Sr | Nixa | 2010 | | 27 | 55 |
| 11 | Eileen Bridget Mcginnis | Jr | Marquette | 2017 | | 32 | 55 |
| 11 | Kelsey Boyd | Jr | Hillsboro | 2017 | | 30 | 55 |
| 11 | Alyson Marcum | So | Bernie | 2017 | | 26 | 55 |
| 16 | Hailey N Johnson | Jr | Republic | 2008 | | 31 | 54 |
| 16 | Addison Purvis | So | Sullivan | 2017 | | 30 | 54 |
| 16 | Hannah Marie Cox | Sr | Sullivan | 2019 | | 32 | 54 |
| 19 | Nicole Hudson | Fr | Webb City | 2005 | | 30 | 53 |
| 19 | Sophia Gentry | Jr | Bishop LeBlond | 2012 | | 29 | 53 |
| 19 | Emily Frankenreiter | Sr | Lutheran South | 2015 | | 28 | 53 |
| 19 | Kelsey Claire Lenox | Jr | Marquette | 2016 | | 29 | 53 |
| 19 | Shelby Ann-Renee Webster | Sr | Camdenton | 2016 | | 31 | 53 |
| 19 | Abigail King | Sr | Christian | 2017 | | 22 | 53 |
| 25 | Brittany Fortner | So | Northwest (Cedar Hill) | 2009 | | 27 | 51 |
| 25 | Maci Moore | So | Trenton | 2018 | | 30 | 51 |
| 25 | Alexi Sanchez | So | Northwest (Cedar Hill) | 2019 | | 32 | 51 |
| 28 | Hannah D Criswell | Fr | Kennett | 2013 | | 26 | 49 |
| 28 | Haidyn Berry | Sr | Webb City | 2020 | | 33 | 49 |
| 30 | Natalie Moore | Fr | Grandview (Hillsboro) | 2018 | | 18 | 43 |
| 31 | Hannah Jansen | Sr | Webster Groves | 2020 | | 18 | 42 |