| Rank | Total | Student | School | Opponent | Date | |
| 1 | 11 | Molly Seabaugh | Advance | Puxico | 5/5/2008 | |
| 2 | 10 | Desiree Cannon | Puxico | Richland (Essex) | 4/13/2004 | (8 inn.) |
| 3 | 8 | Paige Eddington | Doniphan | Koshkonong | 5/5/2016 | |
| 3 | 8 | Kassidy Watts | Sparta | | 4/3/2018 | |
| 5 | 7 | Molly Seabaugh | Advance | Meadow Heights | 5/6/2008 | |
| 5 | 7 | Molly Seabaugh | Advance | Puxico | 5/5/2008 | |
| 5 | 7 | Carissa Jean Martin | DeKalb | Bishop LeBlond | 10/3/2020 | |
| 8 | 6 | Dana Rybolt | South Nodaway | North Andrew | 9/1/1994 | |
| 8 | 6 | Rachel Hall | Newtown-Harris | Green City | 9/28/2002 | |
| 8 | 6 | Haley Merrick | Doniphan | Neelyville | 10/3/2003 | |
| 8 | 6 | Kelli Koehler | Weaubleau | Warsaw | 9/11/2012 | |
| 8 | 6 | Mykaela Alexi Arellanes | Holt | Visitation Academy | 8/28/2013 | |
| 8 | 6 | Samantha J. Waller | Mid-Buchanan | East Buchanan | 9/26/2015 | |
| 14 | 5 | Abigail Rickermann | Festus | | 9/6/2017 | |
| 14 | 5 | Abigail Rickermann | Festus | | 9/13/2019 | vs Perryville |
| 14 | 5 | Piper Schoemehl | Bernie | Campbell | 3/26/2021 | |
| 14 | 5 | Piper Schoemehl | Bernie | Dexter | 4/1/2021 | |
| 14 | 5 | | Bernie | Puxico | 4/15/2021 | |
| 19 | 4 | Katie Collins | Marion C. Early | | 9/18/2018 | |
| 19 | 4 | Piper Schoemehl | Bernie | Central (New Madrid County) | 4/16/2021 | |
| 21 | 3 | Denise Calvin | Southern Boone | | 1/1/1986 | Class 1A-2A |
| 21 | 3 | Karen Pottorff | North Harrison | | 1/1/1993 | Class 1A |
| 21 | 3 | Lindsey Jacoby | Westran | | 1/1/1996 | Class 2A |
| 21 | 3 | Bailey Baird | Lee's Summit | | 1/1/2014 | Class 4 |
| 21 | 3 | Jennifer Morey | Van Buren | | 1/1/2016 | Class 1 |
| 26 | 2 | Molly Garst | Webb City | | 1/1/2004 | Class 3 |
| 26 | 2 | Londyn Backfisch | Kelly | | 1/1/2008 | Class 3 |