| Rank | RBI | Student | School | Opponent | Date | |
| 1 | 11 | Eileen Bridget Mcginnis | Marquette | Fox | 8/28/2017 | |
| 1 | 11 | Camie Vaughn | Cainsville | | 10/16/2019 | |
| 3 | 10 | Maggie Crossno | Senath-Hornersville | Caruthersville | 4/11/2014 | |
| 3 | 10 | Grace Ussery | William Chrisman | St. Teresa's Academy | 9/28/2017 | |
| 3 | 10 | Madison Ryan | Dixon | Climax Springs | 9/15/2022 | 5 inning Game |
| 3 | 10 | Hailey Presley | Marion C. Early | Halfway | 9/10/2022 | |
| 7 | 9 | Shelley Rennison | Sweet Springs | La Monte | 5/13/2003 | |
| 7 | 9 | Megan Feser | Rockwood Summit | Kirkwood | 8/30/2005 | at Affton |
| 7 | 9 | Nicole Hudson | Webb City | Nevada | 10/3/2005 | |
| 7 | 9 | Kelsey Biggs | Seckman | Parkway West | 9/17/2008 | |
| 7 | 9 | Kayla Taylor | Seckman | Kelly | 10/2/2010 | |
| 7 | 9 | Abigail King | Christian | Trinity Catholic | 9/18/2017 | |
| 7 | 9 | Hannah Marie Cox | Sullivan | | 9/24/2019 | vs. New Haven |
| 7 | 9 | Katerina L Wilds | Lee's Summit West | Parkway South | 10/29/2021 | |
| 7 | 9 | Katerina Wilds | Lee's Summit West | Parkway Central | 10/29/2021 | |
| 7 | 9 | Katerina L Wilds | Lee's Summit West | Parkway Central | 10/29/2021 | |
| 7 | 9 | Maddie Jo Preusser | Saxony Lutheran | Herculaneum | 10/17/2024 | |
| 18 | 8 | Amy Woodruff | Gallatin | Stanberry | 9/30/1997 | |
| 18 | 8 | Nicole Beecher | Blue Springs South | William Chrisman | 10/4/2004 | |
| 18 | 8 | Katie B Kroeger | Northwest (Cedar Hill) | Mehlville | 9/25/2009 | |
| 18 | 8 | Madeline Strickland | Seckman | Cor Jesu Academy | 10/3/2012 | |
| 18 | 8 | Jessica Heese | North Platte | East Buchanan | 9/26/2013 | |
| 18 | 8 | Adrienne Compton | Hancock | Bayless | 9/1/2015 | |
| 18 | 8 | Paige Eddington | Doniphan | Corning (Ark.) | 4/26/2016 | |
| 18 | 8 | Tressa Hughes | Dixon | Belle | 9/25/2017 | |
| 18 | 8 | Megan Ann Green | Jefferson City | | 9/4/2018 | |
| 18 | 8 | Gwendolyn D Bostick | Centralia | | 9/29/2018 | |
| 18 | 8 | Natalie Moore | Grandview (Hillsboro) | | 3/18/2019 | |
| 18 | 8 | Lane Petry | Northwest (Cedar Hill) | Lindbergh | 10/6/2020 | |
| 18 | 8 | Maleigh Elizabeth Lemings | Holcomb | Delta | 4/14/2021 | |
| 18 | 8 | Laney Halley | Iberia | Tuscumbia | 10/4/2021 | |
| 18 | 8 | Madison Ryan | Dixon | Richland | 8/31/2022 | |
| 18 | 8 | Elysia Hand | Kearney | Kearney | 10/29/2022 | |
| 18 | 8 | Elysia Hand | Kearney | Helias Catholic | 10/28/2022 | |
| 18 | 8 | Elysia Hand | Kearney | Helias Catholic | 10/28/2022 | |
| 18 | 8 | Ashtyn Reese | Poplar Bluff | Naylor | 9/14/2023 | |
| 18 | 8 | Maizy Sabourin | Hillsboro | Union | 9/22/2025 | |
| 38 | 7 | Courtney Scott | Dixon | Climax Springs | 10/8/2020 | |
| 38 | 7 | Maleigh Lemings | Holcomb | Naylor | 4/7/2023 | |
| 38 | 7 | Jenna Murkin | Kingsville | Windsor | 4/5/2024 | |
| 38 | 7 | Ivy Benson | Twin Rivers | Sikeston | 9/4/2025 | |
| 42 | 6 | Jasmine Taylor | Braymer | Pattonsburg | 9/19/2017 | |
| 42 | 6 | Addison Purvis | Sullivan | | 9/21/2017 | vs. Jefferson |
| 42 | 6 | Alaney Moore | Kelly | | 10/7/2019 | |
| 42 | 6 | Emma Thiltgen | Dixon | Crocker | 10/6/2020 | |
| 42 | 6 | Isabelle Magner | Dixon | Laquey | 9/5/2024 | 3 innings |
| 42 | 6 | Jaylyn Piggott | Iberia | Crocker | 10/4/2024 | |
| 42 | 6 | Bailie Crist | Highland | Knox County | 10/10/2024 | |
| 42 | 6 | Haleigh A Winter | Highland | Knox County | 10/10/2024 | |
| 42 | 6 | Bailie Crist | Highland | Lutheran St. Charles | 9/7/2024 | |
| 42 | 6 | Haleigh A Winter | Highland | Knox County | 10/10/2024 | |
| 42 | 6 | Keera E Rothweiler | Highland | Monroe City | 10/19/2024 | |
| 53 | 5 | Rhonda McIntyre | West Nodaway | | 1/1/1982 | Class 1A-2A |
| 53 | 5 | Nikki Leutkemeyer | St. Elizabeth | | 1/1/1992 | Class 1A |
| 53 | 5 | Bailey Baird | Lee's Summit | | 1/1/2013 | Class 4 |
| 53 | 5 | Addison Purvis | Sullivan | | 9/30/2016 | vs. Marshfield |
| 53 | 5 | Hannah Marie Cox | Sullivan | | 8/31/2016 | @ Windsor |
| 53 | 5 | Addison Purvis | Sullivan | | 9/12/2017 | vs. Pacific |
| 53 | 5 | Hannah Marie Cox | Sullivan | | 9/5/2017 | vs. St. James |
| 53 | 5 | Addison Purvis | Sullivan | | 9/28/2018 | vs. Joplin |
| 53 | 5 | Addison Purvis | Sullivan | | 10/9/2018 | @ Rolla |
| 53 | 5 | Hanna Nicole Johanning | Sullivan | | 9/4/2018 | vs. Owensville |
| 53 | 5 | Addison Purvis | Sullivan | | 9/17/2019 | @ St. Clair |
| 53 | 5 | Grace Glaser | Sullivan | | 9/3/2019 | vs. Borgia |
| 53 | 5 | Victoria Lynn Bradley | Blue Springs South | Raymore-Peculiar | 11/2/2019 | |
| 53 | 5 | Courtney Scott | Dixon | St. Clair | 10/3/2020 | |
| 53 | 5 | Abigail Jamros | Seneca | Aurora | 10/12/2023 | 6 inning game |
| 53 | 5 | Jaylyn Piggott | Iberia | Osage | 9/25/2024 | |
| 53 | 5 | Kinlee Cochran | Iberia | Dixon | 9/26/2024 | |
| 53 | 5 | Adelynn Abell | Highland | Clark County | 9/26/2024 | |
| 71 | 4 | Amber Hayden | Webb City | | 1/1/2004 | Class 3 |
| 71 | 4 | Elizabeth Mosley | Pleasant Hope | | 1/1/2012 | Class 2 |
| 71 | 4 | Logan Vaughan | Kennett | West County | 1/1/2015 | |
| 71 | 4 | Kelly Ivy | Kelly | | 9/6/2019 | |
| 71 | 4 | Kelly Ivy | Kelly | | 9/19/2019 | |
| 71 | 4 | Alaney Moore | Kelly | | 9/28/2019 | |
| 71 | 4 | Alaney Moore | Kelly | Twin Rivers | 10/16/2020 | |
| 71 | 4 | Kimberly Anne Seabaugh | Kelly | DeSoto | 9/4/2020 | |
| 71 | 4 | Alaney Moore | Kelly | Twin Rivers | 10/2/2020 | |
| 71 | 4 | Kendyl Stuckey | Kelly | Chaffee | 10/5/2020 | |
| 71 | 4 | Lauren Turner | Diamond | Kennett | 5/21/2024 | |