| Rank | Total | Student | School | Years |
| 1 | 3 |
Kerry Speaker
Lebanon
| Lebanon High School | 1976, 1977, 1978 |
| 1 | 3 |
Brianna Broderick
Richmond
| Richmond High School | 2000, 2001, 2002 |
| 1 | 3 |
Megan Propeck
Notre Dame de Sion
| Notre Dame de Sion High School | 2017, 2018, 2020 |
| 4 | 2 |
Jill Bertram
Lindbergh
| Lindbergh High School | 1980, 1981 |
| 4 | 2 |
Barb Blanchar
Rock Bridge
| Rock Bridge High School | 1983, 1984 |
| 4 | 2 |
Anne Cain
Glendale
| Glendale High School | 1984, 1985 |
| 4 | 2 |
Kelly Cooper
Notre Dame de Sion
| Notre Dame de Sion High School | 1988, 1989 |
| 4 | 2 |
Robin Buck
St. Joseph's Academy
| St. Joseph's Academy High School | 1990, 1991 |
| 4 | 2 |
Libby Howard
Smith-Cotton
| Smith-Cotton High School | 1992, 1993 |
| 4 | 2 |
Kelsey Meyer
Nerinx Hall
| Nerinx Hall High School | 2003, 2005 |
| 4 | 2 |
Brooke Cusumano
Westminster Christian Academy
| Westminster Christian Academy High School | 2011, 2012 |
| 4 | 2 |
Sarah Bell
Notre Dame (Cape Girardeau)
| Notre Dame (Cape Girardeau) High School | 2016, 2017 |
| 4 | 2 |
Kayla Pfitzner
Springfield Catholic
| Springfield Catholic High School | 2018, 2019 |
| 4 | 2 |
Savannah Lee Thessing
New Covenant Academy
| New Covenant Academy High School | 2020, 2021 |
| 4 | 2 |
Reagan Zibilski
Springfield Catholic
| Springfield Catholic High School | 2020, 2021 |
| 4 | 2 |
Marlene Edgeman
Marshfield
| Marshfield High School | 2021, 2022 |
| 4 | 2 |
Rylee Allred
Ash Grove
| Ash Grove High School | 2023, 2024 |
| 4 | 2 |
Page Bowman
Glendale
| Glendale High School | 2023, 2024 |
| 4 | 2 |
Emree Cameron
Nevada
| Nevada High School | 2023, 2024 |