| Rank | Student | School | Opponent | Date | | Inn | Total |
| 1 | | Francis Howell | Vianney | 6/3/2011 | | 7 | 69 |
| 2 | | St. Clair | Excelsior Springs | 6/5/1999 | | 8 | 52 |
| 3 | | Westminster Christian Academy | Kennett | 6/3/2011 | | 7 | 49 |
| 4 | | Blue Springs | Francis Howell | 6/4/1999 | | 7 | 46 |
| 5 | | Christian Brothers College | Truman | 6/2/1990 | | 7 | 42 |
| 5 | | St. Dominic | Notre Dame (Cape Girardeau) | 5/30/2008 | | 7 | 42 |