| Rank | Student | Grade | School | Year | | G | TD |
| 1 | Steven Willhite | Sr | Pattonsburg | 2019 | | 12 | 112 |
| 2 | Mack J Anderson | Sr | Southwest (Livingston County) | 2019 | | 13 | 92 |
| 3 | Wesley Hughes | Sr | Southwest (Livingston County) | 2020 | | 13 | 84 |
| 4 | Steven Willhite | Jr | Pattonsburg | 2018 | | 12 | 82 |
| 5 | Zane Jacoby | Sr | Westran | 2014 | | 15 | 73 |
| 6 | Kellen Overstreet | Sr | Penney | 2014 | | 14 | 70 |
| 7 | Mack J Anderson | Jr | Southwest (Livingston County) | 2018 | | 11 | 68 |
| 8 | Cole Dilley | Sr | Pattonsburg | 2017 | | 11 | 64 |
| 9 | Derek Aikin | Jr | Penney | 2013 | | 17 | 63 |
| 10 | Lee Flood | Jr | Marionville | 2005 | | 14 | 54 |
| 11 | Caleb Schaffitzel | Jr | Fair Grove | 2008 | | 13 | 53 |
| 11 | Elijah Aston | Sr | Seneca | 2014 | | 15 | 53 |
| 13 | Colten Allen | Jr | Fair Grove | 2009 | | 11 | 52 |
| 14 | Jacob Coffey | Jr | Drexel | 2021 | | 13 | 51 |
| 15 | Dan Kneeshaw | Jr | Branson | 1989 | | 14 | 50 |
| 15 | Caleb Schaffitzel | So | Fair Grove | 2008 | | 12 | 50 |
| 17 | Brayden James Lidgard | So | West Plains | 2017 | | 12 | 41 |
| 18 | Brayden James Lidgard | Jr | West Plains | 2018 | | 13 | 40 |