| Rank | Total | Student | School | Opponent | Date | |
| 1 | 0 | | St. Louis University | East St. Louis Central Catholic, IL | 11/2/1947 | |
| 1 | 0 | | St. Louis University | Christian Brothers College | 11/2/1973 | |
| 1 | 0 | | St. Louis University | Christian Brothers College | 11/9/1979 | |
| 1 | 0 | | Bishop LeBlond | Braymer | 9/17/1993 | |
| 5 | 1 | | Chillicothe | Carrollton | 9/11/1959 | |
| 5 | 1 | | St. Louis University | Alton Marquette, IL | 10/15/1961 | |
| 5 | 1 | | St. Louis University | Ritenour | 10/27/1961 | |
| 5 | 1 | | Vianney | John F. Kennedy | 10/6/1972 | date? |
| 5 | 1 | | Vianney | Bishop DuBourg | 11/7/1975 | date? |
| 5 | 1 | | Chillicothe | Cameron | 9/8/1978 | |
| 5 | 1 | | Herculaneum | Maplewood-Richmond Hts. | 9/16/1988 | |
| 5 | 1 | | Vianney | St. Mary's (St. Louis) | 10/21/1994 | |
| 5 | 1 | | Rich Hill | Liberal | 11/4/1994 | |
| 5 | 1 | | Hillsboro | Festus | 11/4/1997 | |
| 5 | 1 | | Marionville | Strafford | 9/14/2007 | |
| 5 | 1 | | Central (Cape Girardeau) | Poplar Bluff | 10/8/2010 | |
| 5 | 1 | | Smith-Cotton | St. Michael the Archangel | 9/22/2017 | |
| 18 | 2 | | North Shelby | Hardin-Central | 9/10/2021 | |
| 19 | 3 | | South Holt | Miami | 11/1/1988 | |