| Rank | Student | Grade | School | Year | | G | STL |
| 1 | Kenna Rea Walker | Sr | New Bloomfield | 1988-1989 | | 31 | 258 |
| 2 | Kim Woodruff | Sr | St. James | 1996-1997 | | 27 | 257 |
| 3 | Madison Carvajal | Fr | Meadville | 2022-2023 | | 29 | 249 |
| 4 | Kenna Rae Walker | So | New Bloomfield | 1996-1997 | | 27 | 236 |
| 5 | Danielle Freeman | Sr | Soldan International Studies | 1988-1989 | | 24 | 234 |
| 5 | Madison Carvajal | So | Meadville | 2023-2024 | | 29 | 234 |
| 7 | Kim Woodruff | Jr | St. James | 1995-1996 | | 29 | 210 |
| 8 | Kim Woodruff | So | St. James | 1994-1995 | | 32 | 208 |
| 9 | LeAnn Peckham | Sr | Sarcoxie | 1983-1984 | | 27 | 200 |
| 9 | Donna Simon | Sr | Duchesne | 1995-1996 | | 28 | 200 |
| 11 | Iesia Sutton | Jr | Berkeley High School | 2001-2002 | | 24 | 196 |
| 11 | Jade Berry | Sr | Delta | 2024-2025 | | 29 | 196 |
| 13 | Carrie Dickinson | Sr | DeSoto | 1991-1992 | | 28 | 194 |
| 13 | Lacy Stokes | Sr | Mt. Vernon | 2020-2021 | | 32 | 194 |
| 15 | Korrie Holcer | Sr | Meadville | 2023-2024 | | 29 | 187 |
| 16 | Lacy Stokes | Fr | Mt. Vernon | 2017-2018 | | 30 | 183 |
| 17 | Jordann Plummer | So | Cardinal Ritter | 2002-2003 | | 24 | 179 |
| 18 | Carlie Sanders | Sr | Hillsboro | 2017-2018 | | 26 | 175 |
| 19 | Jada Bentley | Sr | Beaumont | 2006-2007 | | 22 | 173 |
| 20 | Maddie Ayers | Fr | South Iron | 2019-2020 | | 30 | 171 |
| 21 | Crystal Smith | Jr | Jasper | 2023-2024 | | 26 | 165 |
| 22 | Carlie Sanders | Jr | Hillsboro | 2016-2017 | | 26 | 158 |
| 23 | Keylie Beane | Sr | Lathrop | 2023-2024 | | 28 | 155 |
| 24 | Jade Berry | Jr | Delta | 2023-2024 | | 30 | 154 |
| 25 | Victoria Nauman | Sr | Mound City | 2018-2019 | | 28 | 152 |
| 25 | Korrie Holcer | Jr | Meadville | 2022-2023 | | 30 | 152 |
| 27 | Nikki Ilg | Sr | St. John the Baptist | 2001-2002 | | 20 | 151 |
| 28 | Kelsi McQuinn | Sr | Jefferson (Conception) | 2016-2017 | | 30 | 147 |
| 29 | Paige Carvajal | Jr | Meadville | 2022-2023 | | 30 | 142 |
| 30 | Lilyan Carr | So | Spokane | 2024-2025 | | 27 | 133 |
| 31 | Crystal Smith | So | Jasper | 2022-2023 | | 24 | 132 |